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CART Peptides: Modulators of Mesolimbic Dopamine, Feeding, and Stress
aYerkes National Primate Research Center, Division of Neuroscience, Emory University, Atlanta, Georgia 30329, USA bDepartment of Pediatrics, Second University of Naples, Naples 80138, Italy
Address for correspondence: Michael J. Kuhar, Ph.D., Yerkes National Primate Research Center, Division of Neuroscience, 954 N. Gatewood Rd., Emory University, Atlanta, GA 30329. Voice: 404-727-1737; fax: 404-727-3278. mkuhar{at}emory.edu Ann. N.Y. Acad. Sci. 1025: 363-369 (2004).
CART peptides have been shown to be peptide neurotransmitters and endocrine factors in a series of cumulative studies over the past eight years or so. This brief review touches on three aspects of CART: CART as a mediator or modulator of mesolimbic dopamine, CART's regulation by glucocorticoids, and CART as a regulator of feeding, satiety, and body weight. There have been several recent reviews and publications on various aspects of CART peptides. These aspects include the sequence and numbering of the peptides, and their structure, processing, and roles in various physiologic processes.
Key Words: feeding • stress • satiety • body weight • reward This article has been cited by other articles:
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