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Issue 1030 coverSignal Transduction Pathways, Chromatin Structures, and Gene Expression Mechanisms as Therapeutic Targets Volume 1030 published December 2004
Ann. N.Y. Acad. Sci. 1030: 449–457 (2004). doi: 10.1196/annals.1329.056
Copyright © 2004 by the New York Academy of Sciences
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Hypoxia/Anoxia as Signaling for Increased Alcohol Dehydrogenase Activity in Saffron (Crocus sativus L.) Corm

EZZATOLLAH KEYHANIa AND JACQUELINE KEYHANI

Laboratory for Life Sciences, Saadat Abade, 19979 Tehran, Iran

aAddress for correspondence: Dr. E. Keyhani, Laboratory for Life Sciences, Saadat Abade, Sarve Sharghi 34, 19979 Tehran, Iran. Voice: +98-21-207-4804; fax: +98-21-640-4680. e-mail: keyhanius2002{at}yahoo.com

Alcohol dehydrogenase, NAD-dependent lactate dehydrogenase, and NAD-independent lactate dehydrogenase activities were investigated in corms cultivated in normoxic and hypoxic/anoxic conditions. Depending on the developmental stage, hypoxia/anoxia was a signal for increase in either alcohol dehydrogenase or NAD-dependent lactate dehydrogenase. NAD-independent lactate dehydrogenase contributed to the recycling of lactate, thus preventing acidosis.

Key Words: saffron • hypoxia/anoxia • alcohol dehydrogenase • NAD-dependent lactate dehydrogenase • NAD-independent lactate dehydrogenase • lactate loop




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E. KEYHANI, L. GHAMSARI, J. KEYHANI, and M. HADIZADEH
Antioxidant Enzymes during Hypoxia-Anoxia Signaling Events in Crocus sativus L. Corm
Ann. N.Y. Acad. Sci., December 1, 2006; 1091(1): 65 - 75.
[Abstract] [Full Text] [PDF]



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