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bCenter of Tobacco Control Research, Odense, Denmark cDepartment of Endocrinology and Department of Surgery, Aalborg University Hospital, Denmark dCancer Society, Copenhagen, Denmark
aAddress for correspondence: Finn Edler von Eyben, Center of Tobacco Control Research, Birkevej 17, 5230 Odense M, Denmark. Voice: 45 66145862. e-mail: finnvon{at}mail.tele.dk
Extent of intra-abdominal fat had significant linear relations with six metabolic coronary risk factors: systolic and diastolic blood pressure, fasting blood concentrations of glucose, high density lipoprotein (HDL) cholesterol, triglyceride, and plasminogen activator inhibitor-1. Tumor necrosis factor-
and adiponectin can be biological mediators from the intra-abdominal fat to the metabolic coronary risk factors. Complementarily, we describe a new study that will analyze the gene expression in intra-abdominal and subcutaneous fat on mRNA and protein level using high throughput methods. The study will elucidate further whether intra-abdominal obesity is the common denominator for the different components of the metabolic syndrome.
Key Words: obesity coronary risk factors metabolic syndrome microarray 2-dimensional gel electrophoresis cytokines This article has been cited by other articles:
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