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Issue 1039 coverClinical and Basic Oculomotor Research: In Honor of David S. Zee Volume 1039 published April 2005
Ann. N.Y. Acad. Sci. 1039: 567–570 (2005). doi: 10.1196/annals.1325.069
Copyright © 2005 by the New York Academy of Sciences
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Pontine Lesions May Cause Selective Deficits of "Slow" Vergence Eye Movements

H RAMBOLD, G NEUMANN, T SANDER AND C HELMCHEN

Department of Neurology, University of Luebeck, 23538 Luebeck, Germany

Address for correspondence: H. Rambold, Dept. of Neurology, University of Luebeck, Ratzeburger Allee 160, 23538 Luebeck, Germany. Voice: +451-500-3709; fax: +451-500-2489. Holger.Rambold{at}neuro.uni-luebeck.de

To address the role of pontine nuclei in vergence control, eye movements to ramp (`slow vergence') and step targets (`fast vergence') were recorded in two patients with unilateral mediolateral pontine infarctions and in ten healthy controls. `Slow' vergence and conjugate smooth pursuit eye movements were impaired while `fast' vergence was not. We conclude that like smooth pursuit signals, vergence signals are distributed in the pontine nuclei.

Key Words: vergence • pontine infarction • smooth pursuit






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