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Issue 1044 coverHEMATOPOIETIC STEM CELLS V Volume 1044 published June 2005
Ann. N.Y. Acad. Sci. 1044: 132–138 (2005). doi: 10.1196/annals.1349.017
Copyright © 2005 by the New York Academy of Sciences
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Articles by LEMISCHKA, I. R.
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Articles by LEMISCHKA, I. R.
Stem Cell Biology: A View toward the Future

IHOR R. LEMISCHKA

Department of Molecular Biology, Princeton University, Princeton, New Jersey 08544, USA

Address for correspondence: Ihor R. Lemischka, Department of Molecular Biology, Washington Road, Princeton University, Princeton NJ 08544. Voice: 609-258-2838; fax: 609-258-1704. ilemischka{at}molbio.princeton.edu

In this essay I have attempted to provide clues relating to novel research avenues that are likely to have a broad impact on the field of stem cell biology. The specific examples, drawn from other areas, are meant to be instructive and are representative of many more similar efforts. I have suggested that the new areas of systems and synthetic biology may provide a truly deep level of understanding for many aspects of how stem cells make fate choices. Successful application of new avenues will require an integrative approach that combines experimental and computational techniques.

Key Words: stem cell research • systems biology • synthetic biology • hematopoietic stem cell • somatic stem cell




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