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Issue 1048 coverBiophysics from Molecules to Brain: In Memory of Radoslav K. Andjus Volume 1048 published June 2005
Ann. N.Y. Acad. Sci. 1048: 422–426 (2005). doi: 10.1196/annals.1342.053
Copyright © 2005 by the New York Academy of Sciences
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Correlation Properties and Regularity of Heart Period Time Series: Influence of Posture and Heart Disease

VESNA VUKSANOVIC AND VERA GAL

Institute of Biophysics, Faculty of Medicine, University of Belgrade, Belgrade, Serbia and Montenegro

Address for correspondence: Vesna Vuksanovic, Institute for Biophysics, Faculty of Medicine, Visegradska 26/2, 11000 Belgrade, Serbia and Montenegro. Voice: 381113615767; fax: 381113615767. vvesna{at}eunet.yu

Nonlinear measures of heart period variability (HPV) were determined in supine rest and standing posture in children and young adults with heart disease and compared to the control. The aim was to study influence of posture and heart disease on heart period dynamics. It was found that standing increases short-term scaling exponent in all subjects and decreases sample entropy in healthy and less severely ill patients. Severely ill patients compared to control have higher short-term scaling exponent in supine. Changes in nonlinear measures of HPV upon standing are more pronounced in healthy than diseased subjects due to different vagal activity.

Key Words: heart rate variability • DFA • SampEn • active standing • children and young adults






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