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Issue 1057 coverReversal of Aging: Resetting the Pineal Clock Volume 1057 published December 2005
Ann. N.Y. Acad. Sci. 1057: 492–505 (2005). doi: 10.1196/annals.1322.038
Copyright © 2005 by the New York Academy of Sciences
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Articles by VITETTA, L
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Articles by VITETTA, L
Articles by SALI, A
Mind-Body Medicine: Stress and Its Impact on Overall Health and Longevity

L VITETTAa, B ANTONb, F CORTIZOc AND A SALIc

aCentre for Molecular Biology and Medicine, Epworth Hospital Medical Centre, Melbourne, Australia
bPathLab, Melbourne, Australia
cNational Institute of Integrative Medicine, Swinburne University, Melbourne, Australia

Address for correspondence: Dr. Luis Vitetta, Associate Professor and Senior Research Fellow, Centre for Molecular Biology and Medicine, Epworth Medical Centre, 185-187 Hoddle St. Richmond, Melbourne, Victoria, Australia 3121. Voice: +61 3 9426 4200; fax: +61 3 9426 4201. lvitetta{at}cmbm.com.au

The belief that adverse life stressors and the emotional states that can lead to major negative impacts on an individual's body functions and hence health has been held since antiquity. Adverse health outcomes such as coronary heart disease, gastrointestinal distress, and cancer have been linked to unresolved lifestyle stresses that can be expressed as a negative impact on human survival and ultimately a decrease of the human life span. Psychological modulation of immune function is now a well-established phenomenon, with much of the relevant literature published within the last 50 years. Psychoneuroimmunology and psychoneuroendocrinology embrace the scientific evidence of research of the mind with that of endocrinology, neurology and immunology, whereby the brain and body communicate with each other in a multidirectional flow of information that consists of hormones, neurotransmitters/neuropeptides, and cytokines. Advances in mind-body medicine research together with healthy nutrition and lifestyle choices can have a significant impact on health maintenance and disease prevention and hence the prolongation of the human life span.

Key Words: mind-body medicine • psychoneuroimmunology • psychoneuroendocrinology • psychosocial stress • longevity




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