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Issue 1078 coverCentury of Rickettsiology: Emerging, Reemerging Rickettsioses, Molecular Diagnostics, and Emerging Veterinary Rickettsioses Volume 1078 published October 2006
Ann. N.Y. Acad. Sci. 1078: 106–109 (2006). doi: 10.1196/annals.1374.015
Copyright © 2006 by the New York Academy of Sciences
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Part I. Epidemiology of Rickettsial Disease

Human Granulocytic Anaplasmosis in Northeastern Italy

ANNA BELTRAMEa, MAURIZIO RUSCIOb, ALESSANDRA ARZESEc, GIADA RORATOa, CAMILLA NEGRIa, ANGELA LONDEROa, MASSIMO CRAPISa, LUIGIA SCUDELLERa AND PIERLUIGI VIALEa

a Clinic of Infectious Diseases, Department of Clinical and Morphological Research, School of Medicine, University of Udine, Udine 33100, Italy b Microbiology Department, Hospital of S. Daniele, S. Daniele 33038, Italy c Institute of Microbiology, University of Udine, Udine 33100, Italy

Key Words: human granulocytic anaplasmosis • tick-borne infection • seroprevalence • Italy

Address for correspondence: Anna Beltrame, Department of Infectious Disease, Via Colugna No. 50, 33100 Udine, Italy. Voice: +39-0432-55-9355; fax: +39-0432-55-9360.  e-mail: anna.beltrame{at}med.uniud.it

Sporadic cases of human granulocytic anaplasmosis (HGA) have been reported in areas with a high prevalence of tick-borne diseases (TBDs) in Europe. We aimed at estimating the sero-prevalance of A. phagocytophilum and other TBDs in northeastern Italy in outpatients with a history of recent tick bite or suspected TBD. In the 1-year study, 79 patients were enrolled and 30 (38%) received a diagnosis of TBD: 24 (30%) with Lyme desease and 5 (6%) with HGE. Our findings indicate the presence of HGA in northernsterm Italy; so, since co-infection with Lyme disease appeared to be frequent, physicians assessing patients after a tick bite should consider HGA in the diagnosis.






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