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a Department of Biochemistry, Yong Loo Lin School of Medicine, National University of Singapore, Kent Ridge, Singapore 119260
Key Words: Psoralea corylifolia L • mitochondrial complex I • proteasome • oxidative stress
Address for correspondence: Barry Halliwell, National University of Singapore, University Hall, Lee Kong Chian Wing, UHL 05-02G, 21 Lower Kent Ridge Road, Singapore 119077. Voice: +65-6516-3247; fax: +65-6775-2207. bchbh{at}nus.edu.sg
The growing interest in alternative medicines, including traditional medicinal plants, has caused some health concerns due to poor awareness in the general population of the possible side effects from inappropriate practices. Psoralea corylifolia L. has been used in Chinese and Indian traditional medicine for the treatment of various inflammatory diseases of the skin and to improve vitality. Our data show that the extract obtained from the seeds of Psoralea corylifolia L. decreased mitochondrial complex I and proteasome activities; and oxidative stress might be an early event.
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