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Issue 1103 coverHow Do We Best Employ Animal Models for Type 1 Diabetes and Multiple Sclerosis? Volume 1103 published April 2007
Ann. N.Y. Acad. Sci. 1103: 33–44 (2007). doi: 10.1196/annals.1394.016
Copyright © 2007 by the New York Academy of Sciences
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Articles by ROSSINI, A. A.
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Articles by ROSSINI, A. A.
Articles by GREINER, D. L.

Part I. Controversies Surrounding the Use of Animal Models in Type 1 Diabetes and Multiple Sclerosis

Diabetes Research in Jeopardy

The Extinction of Clinical Diabetes Researchers

ALDO A. ROSSINIa AND DALE L. GREINERa

a University of Massachusetts Medical School, Worcester, Massachusetts, USA

Key Words: diabetes researcher • new investigator • pediatric diabetes • type 1 diabetes • physician scientist

Address for correspondence: Aldo A. Rossini, M.D., Diabetes Division, University of Massachusetts Medical School, 373 Plantation Street, Suite 218, Worcester, MA 01605. Voice: 508-856-3800; fax: 508-856-4093.  Aldo.rossini{at}umassmed.edu

Finding a cure for an autoimmune disease, such as diabetes, must be viewed as a marathon. Although there are occasional quick sprints forward on the road to discovery, the bulk of research is carried out steadily over time. Over the years, researchers have made progressive strides toward a cure, but our field is now facing a crisis. We need youthful researchers with fresh new perspectives to carry on the work started by forerunners in the field. In fact, many young people never get the opportunity to work in a scientific field. Of those who do choose to study science, after receiving a bachelor's degree in that field, only 4% eventually receive their doctorate. There are many reasons for the abrupt end of the academic path for these students. Perhaps they are stymied in their education, frustrated by the lack of grant support and mentorship provided to young scientists. On average, a scientist receives his or her first NIH R01 award at the age of 43 years. Moreover, many young researchers lack the mentorship they seek from more established scientists. This hurdle can be overcome by providing young scientists the ability to work unreservedly with other mature scientists. Ideally, a Diabetes Research Center needs to be geared toward facilitating collaboration and free exchange of ideas to promote the maturation of young scientists. Additionally, this environment, can offer young scientists the resources that would otherwise be unavailable to them. This concept is fundamental to creating more experienced and prolific scientists in the field of diabetes.






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