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Issue 1125 coverIncredible Anaerobes From Physiology to Genomics to Fuels Volume 1125 published April 2008
Ann. N.Y. Acad. Sci. 1125: 267–279 (2008). doi: 10.1196/annals.1419.002
Copyright © 2008 by the New York Academy of Sciences
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Part V. Cellulolytic Anaerobes and Their Cellulolytic Enzymes

Cellulases of Mesophilic Microorganisms

Cellulosome and Noncellulosome Producers

ROY H. DOIa

a Section of Molecular and Cellular Biology, University of California, Davis, California, USA

Key Words: cellulosomes • cellulases • hemicellulases • Clostridia • mesophiles

Address for correspondence: Roy H. Doi, Section of Molecular and Cellular Biology, University of California, One Shields Avenue, Davis, CA 95616. Voice: (530) 752-3191.  rhdoi{at}ucdavis.edu

The cellulolytic activity of mesophilic bacteria and fungi is described, with special emphasis on the large extracellular enzyme complex called the cellulosome. The cellulosome is composed of a scaffolding protein, which is attached to various cellulolytic and hemicellulolytic enzymes, and this complex allows the organisms to degrade plant cell walls very efficently. The enzymes include a variety of cellulases, hemicellulases, and pectinases that work synergistically to degrade complex cell-wall molecules.






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