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Issue 1127 coverAssessment of Human Reproductive Function Volume 1127 published April 2008
Ann. N.Y. Acad. Sci. 1127: 134–139 (2008). doi: 10.1196/annals.1434.002
Copyright © 2008 by the New York Academy of Sciences
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Articles by BARLOW, D. H.
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Articles by BARLOW, D. H.

Part VII. Medical Intervention and the Endocrinology of Menopause, Obesity, and Pain Management

The Medical Management of Menopause

To Treat or Not To Treat?

DAVID H. BARLOWa

a Executive Dean of Medicine, Professor of Reproductive Medicine, The University of Glasgow, Glasgow, Scotland, United Kingdom

Key Words: hormone therapy • estrogen • progestogen • progestin • vasomotor symptoms • menopause • postmenopause • cardiovascular disease • coronary heart disease • stroke • breast cancer • hysterectomy • randomized controlled trial • osteoporosis • fracture

Address for correspondence: Professor David H. Barlow, Wolfson Medical School Building, University of Glasgow, University Avenue, Glasgow G12 8QQ, Scotland, UK. Voice: +44-141-330-3362.  execdean{at}clinmed.gla.ac.uk

The evidence concerning the effects of hormone therapy (HT) has been greatly expanded by the publication of very large randomized controlled trials. A consequence has been concern among women about the risks of HT such that the number of menopausal women using HT for relief of menopausal symptoms has declined. It is now appropriate to look at the best evidence available and to consider current policies. Women in the early postmenopausal phase, generally younger than 60 years of age, who are troubled by menopausal symptoms should be reassured that, for their circumstances, medical management of menopause in the form of HT is appropriate. If they go on to use HT for several years, it is possible that they will experience skeletal and coronary health benefits, but the evidence for such benefits is a matter of ongoing debate.






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