 | NEUROPEPTIDES: STRUCTURE AND FUNCTION IN BIOLOGY AND BEHAVIOR
Copyright © 1999 by the New York Academy of Sciences
description
Annals of the New York Academy of Sciences 897:311-329 (1999)
© 1999 New York Academy of Sciences
Allatostatins: A Growing Family of Neuropeptides with Structural and Functional Diversity
W. G. BENDENAa,b,
B. C. DONLYc AND
S. S. TOBEd
bDepartment of Biology, Queen's University, Kingston, Ontario, Canada K7L 3N6
cAgriculture and Agri-Food Canada, London, Ontario, Canada N5V 4T3
dDepartment of Zoology, University of Toronto, Toronto, Ontario, Canada M5S 1A1
aAddress for correspondence: 613-533-6121 (voice); 613-533-6617 (fax). e-mail: bendenaw{at}biology.queensu.ca
The high degree of conservation of the core sequence of the "cockroach-types" of AST and their widespread distribution suggest that they should be considered a ubiquitous family of peptides within the invertebrates, regulating a range of important physiological processes. These functional processes, by either neural or humoral routes of action, include the inhibition of endocrine function, interneuronal functions, neuromodulatory roles, myotropic and myoendocrine roles, and direct action on biosynthetic pathways. The myomodulatory function appears to be conserved through evolutionary time, whereas the JH inhibitory activity appears to be confined to specific orders. This suggests that the myomodulatory role was the more ancestral of these two particular functions. Certainly, further purification and gene cloning as a means to precursor identification and functional analysis will be a prerequisite to understanding the diverse functions of this peptide family.
This article has been cited by other articles:
|
|
|
|
 
W. G. Bendena, J. R. Boudreau, T. Papanicolaou, M. Maltby, S. S. Tobe, and I. D. Chin-Sang
A Caenorhabditis elegans allatostatin/galanin-like receptor NPR-9 inhibits local search behavior in response to feeding cues
PNAS,
January 29, 2008;
105(4):
1339 - 1342.
[Abstract]
[Full Text]
[PDF]
|
|
|
|
|
|
|
Y. Li, S. Hernandez-Martinez, F. Fernandez, J. G. Mayoral, P. Topalis, H. Priestap, M. Perez, A. Navare, and F. G. Noriega
Biochemical, Molecular, and Functional Characterization of PISCF-Allatostatin, a Regulator of Juvenile Hormone Biosynthesis in the Mosquito Aedes aegypti
J. Biol. Chem.,
November 10, 2006;
281(45):
34048 - 34055.
[Abstract]
[Full Text]
[PDF]
|
|
|
|
|
|
|
A. J. Zera
The Endocrine Regulation of Wing Polymorphism in Insects: State of the Art, Recent Surprises, and Future Directions
Integr. Comp. Biol.,
November 1, 2003;
43(5):
607 - 616.
[Abstract]
[Full Text]
[PDF]
|
|
|
|
|
|
|
T. Secher, C. Lenz, G. Cazzamali, G. Sorensen, M. Williamson, G. N. Hansen, P. Svane, and C. J. P. Grimmelikhuijzen
Molecular Cloning of a Functional Allatostatin Gut/Brain Receptor and an Allatostatin Preprohormone from the Silkworm Bombyx mori
J. Biol. Chem.,
December 7, 2001;
276(50):
47052 - 47060.
[Abstract]
[Full Text]
[PDF]
|
|
|
|
|
|
|
A. N. Nathoo, R. A. Moeller, B. A. Westlund, and A. C. Hart
Identification of neuropeptide-like protein gene families in Caenorhabditiselegans and other species
PNAS,
November 20, 2001;
98(24):
14000 - 14005.
[Abstract]
[Full Text]
[PDF]
|
|
|
|
|
|
|
T. Brody and A. Cravchik
Drosophila melanogaster G Protein-coupled Receptors
J. Cell Biol.,
July 24, 2000;
150(2):
F83 - F88.
[Abstract]
[Full Text]
[PDF]
|
|
|
|
