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Issue 903 coverVASCULAR FACTORS IN ALZHEIMER'S DISEASE Copyright © 2000 by the New York Academy of Sciences
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Articles by AGÜERO-TORRES, H.
Articles by WINBLAD, B.
Annals of the New York Academy of Sciences 903:547-552 (2000)
© 2000 New York Academy of Sciences

Alzheimer's Disease and Vascular Dementia: Some Points of Confluence

HEDDA AGÜERO-TORRESa,b AND BENGT WINBLADa,b

aStockholm Gerontology Research Center, Occupational Therapy, and Elderly Care Research, Division of Geriatric Medicine, Karolinska Institute, S-11382 Stockholm, Sweden
bDepartment of Clinical Neuroscience, Occupational Therapy, and Elderly Care Research, Division of Geriatric Medicine, Karolinska Institute, S-11382 Stockholm, Sweden

aAddress for correspondence: Hedda Agüero-Torres, MD, PhD, Stockholm Gerontology Research Center, 'The Kungsholmen Project', Box 6401, S-11382 Stockholm, Sweden. Tel.: +46 8 6905854; fax: +46 8 6905954.
e-mail: Hedda.Aguero-Eklund{at}neurotec.ki.se

The lack of biologic markers for Alzheimer's disease and vascular dementia, the controversy regarding the definition of vascular dementia, and the new evidence of vascular risk factors for Alzheimer's disease suggest that the traditional differentiation between Alzheimer's disease and vascular dementia is no longer very clear. We believe that both vascular and degenerative mechanisms contribute to the development of dementia, especially in very old age. The question of whether they are two independent parallel processes or interacting pathologies needs to be clarified.




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