KAREL PACAK and GRAEME EISENHOFER

Preface

Ann NY Acad Sci 2006 1073: xv. [Full Text] [PDF]  

Part I. Presentation and Differential Diagnosis:

WILLIAM M MANGER

An Overview of Pheochromocytoma: History, Current Concepts, Vagaries, and Diagnostic Challenges

Ann NY Acad Sci 2006 1073: 1-20. [Abstract] [Full Text] [PDF]  

WILLIAM F YOUNG, JR

Paragangliomas: Clinical Overview

Ann NY Acad Sci 2006 1073: 21-29. [Abstract] [Full Text] [PDF]  

MARTA BARONTINI, GLORIA LEVIN, and GABRIELA SANSO

Characteristics of Pheochromocytoma in a 4- to 20-Year-Old Population

Ann NY Acad Sci 2006 1073: 30-37. [Abstract] [Full Text] [PDF]  

ANNA A KASPERLIK-ZALUSKA, ELZBIETA ROSLONOWSKA, JADWIGA SLOWINSKA-SRZEDNICKA, MACIEJ OTTO, ANDRZEJ CICHOCKI, JAROSLAW CWIKLA, RAFAL SLAPA, and GRAEME EISENHOFER

1,111 Patients with Adrenal Incidentalomas Observed at a Single Endocrinological Center: Incidence of Chromaffin Tumors

Ann NY Acad Sci 2006 1073: 38-46. [Abstract] [Full Text] [PDF]  

DEBBIE L COHEN, DOUGLAS FRAKER, and RAYMOND R TOWNSEND

Lack of Symptoms in Patients with Histologic Evidence of Pheochromocytoma: A Diagnostic Challenge

Ann NY Acad Sci 2006 1073: 47-51. [Abstract] [Full Text] [PDF]  

HOLGER S WILLENBERG, JOACHIM FELDKAMP, REINER LEHMANN, MATTHIAS SCHOTT, PETER E GORETZKI, and WERNER A SCHERBAUM

A Case of Catecholamine and Glucocorticoid Excess Syndrome Due to a Corticotropin-Secreting Paraganglioma

Ann NY Acad Sci 2006 1073: 52-58. [Abstract] [Full Text] [PDF]  

HENDRICKS H WHITMAN, III, ELLIOT K FISHMAN, KJELL ÖBERG, JOSEPH M WILDMAN, and ANDREA L LONG

Catecholamine-Secreting Metastatic Carcinoid as Differential Diagnosis in Pheochromocytoma: Clinical, Laboratory, and Imaging Clues in the Search for the Lurking Neuroendocrine Tumor (NET)

Ann NY Acad Sci 2006 1073: 59-78. [Abstract] [Full Text] [PDF]  

ELZBIETA DABROWSKA, JACEK LEWANDOWSKI, PIOTR JEDRUSIK, BARTOSZ SYMONIDES, BOZENA WOCIAL, MARIUSZ LAPINSKI, and ZBIGNIEW GACIONG

Catecholamine Excretion and Circadian Blood Pressure Profile in Patients with Pheochromocytoma

Ann NY Acad Sci 2006 1073: 79-85. [Abstract] [Full Text] [PDF]  

TOMÁS ZELINKA, KAREL PACAK, and JIRÍ WIDIMSKY, JR

Characteristics of Blood Pressure in Pheochromocytoma

Ann NY Acad Sci 2006 1073: 86-93. [Abstract] [Full Text] [PDF]  

Part II. Genetics: Increasing Importance for Clinical Decision Making:

STEFAN R BORNSTEIN and ANNE-PAULE GIMENEZ-ROQUEPLO

Genetic Testing in Pheochromocytoma: Increasing Importance for Clinical Decision Making

Ann NY Acad Sci 2006 1073: 94-103. [Abstract] [Full Text] [PDF]  

DIANA E BENN, ANNE LOUISE RICHARDSON, DEBORAH J MARSH, and BRUCE G ROBINSON

Genetic Testing in Pheochromocytoma- and Paraganglioma-Associated Syndromes

Ann NY Acad Sci 2006 1073: 104-111. [Abstract] [Full Text] [PDF]  

ANNE-PAULE GIMENEZ-ROQUEPLO

New Advances in the Genetics of Pheochromocytoma and Paraganglioma Syndromes

Ann NY Acad Sci 2006 1073: 112-121. [Abstract] [Full Text] [PDF]  

BIRKE BAUSCH, CARSTEN C BOEDEKER, ANSGAR BERLIS, INGO BRINK, MARKUS CYBULLA, MARTIN K WALZ, ANDRZEJ JANUSZEWICZ, CLAUDIO LETIZIA, GIUSEPPE OPOCHER, CHARIS ENG, and HARTMUT P.H NEUMANN

Genetic and Clinical Investigation of Pheochromocytoma: A 22-Year Experience, from Freiburg, Germany to International Effort

Ann NY Acad Sci 2006 1073: 122-137. [Abstract] [Full Text] [PDF]  

E KORPERSHOEK, F. H VAN NEDERVEEN, H DANNENBERG, B. J PETRI, P KOMMINOTH, A PERREN, J. W LENDERS, A. A VERHOFSTAD, W. W DE HERDER, R. R DE KRIJGER, and W. N. M DINJENS

Genetic Analyses of Apparently Sporadic Pheochromocytomas: The Rotterdam Experience

Ann NY Acad Sci 2006 1073: 138-148. [Abstract] [Full Text] [PDF]  

GIUSEPPE OPOCHER, FRANCESCA SCHIAVI, MAURIZIO IACOBONE, ANTONIO TONIATO, SABINA SATTAROVA, ZORAN ERLIC, MADDALENA MARTELLA, CATERINA MIAN, ISABELLA MERANTE BOSCHIN, LAURA ZAMBONIN, PAOLA DE LAZZARI, ALESSANDRA MURGIA, MARIA ROSA PELIZZO, GENNARO FAVIA, and FRANCO MANTERO

Familial Nonsyndromic Pheochromocytoma

Ann NY Acad Sci 2006 1073: 149-155. [Abstract] [Full Text] [PDF]  

M CASTELLANO, L MORI, M GIACCHÈ, E AGLIOZZO, R TOSINI, A PANAROTTO, C CAPPELLI, P MULATERO, D CUMETTI, F VEGLIO, and E AGABITI-ROSEI

Genetic Mutation Screening in an Italian Cohort of Nonsyndromic Pheochromocytoma/Paraganglioma Patients

Ann NY Acad Sci 2006 1073: 156-165. [Abstract] [Full Text] [PDF]  

RONALD R DE KRIJGER, FRANCIEN H VAN NEDERVEEN, ESTHER KORPERSHOEK, WOUTER W DE HERDER, SABINE M.P.F DE MUINCK KEIZER-SCHRAMA, and WINAND N.M DINJENS

Frequent Genetic Changes in Childhood Pheochromocytomas

Ann NY Acad Sci 2006 1073: 166-176. [Abstract] [Full Text] [PDF]  

FRANCIEN H VAN NEDERVEEN, WINAND N. M DINJENS, ESTHER KORPERSHOEK, and RONALD R DE KRIJGER

The Occurrence of SDHB Gene Mutations in Pheochromocytoma

Ann NY Acad Sci 2006 1073: 177-182. [Abstract] [Full Text] [PDF]  

M MANNELLI, L SIMI, T ERCOLINO, M.S GAGLIANÒ, L BECHERINI, S VINCI, R SESTINI, F GENSINI, P PINZANI, M MASCALCHI, L GUERRINI, C PRATESI, G NESI, F TORTI, F CIPOLLINI, G.P BERNINI, and M GENUARDI

SDH Mutations in Patients Affected by Paraganglioma Syndromes: A Personal Experience

Ann NY Acad Sci 2006 1073: 183-189. [Abstract] [Full Text] [PDF]  

FRANCESCA SCHIAVI, THEODOROS SAVVOUKIDIS, FRANCO TRABALZINI, FRANCO GREGO, MICHELE PIAZZA, PIETRO AMISTÀ, SERENA DEMATTÈ, ANTONELLA DEL PIANO, MARIA ENRICA CECCHINI, ZORAN ERLIC, PAOLA DE LAZZARI, FRANCO MANTERO, and GIUSEPPE OPOCHER

Paraganglioma Syndrome: SDHB, SDHC, and SDHD Mutations in Head and Neck Paragangliomas

Ann NY Acad Sci 2006 1073: 190-197. [Abstract] [Full Text] [PDF]  

LIBERO SANTARPIA, DANIELA LAPA, and SALVATORE BENVENGA

Germline Mutation of von Hippel–Lindau (VHL) Gene 695 G>A (R161Q) in a Patient with a Peculiar Phenotype with Type 2C VHL Syndrome

Ann NY Acad Sci 2006 1073: 198-202. [Abstract] [Full Text] [PDF]  

AN-LI TONG, ZHENG-PEI ZENG, HAN-ZHONG LI, DI YANG, LIN LU, MING LI, YA-RU ZHOU, JING ZHANG, SHI CHEN, and WEI LIANG

Von Hippel–Lindau Gene Mutation in Non-Syndromic Familial Pheochromocytomas

Ann NY Acad Sci 2006 1073: 203-207. [Abstract] [Full Text] [PDF]  

Part III. Tumor Biology, Molecular Pathways, and Genotype Phenotype Relationships:

PATRICIA L.M DAHIA FOR THE FAMILIAL PHEOCHROMOCYTOMA CONSORTIUM

Transcription Association of VHL and SDH Mutations Link Hypoxia and Oxidoreductase Signals in Pheochromocytomas

Ann NY Acad Sci 2006 1073: 208-220. [Abstract] [Full Text] [PDF]  

BORA E BAYSAL

A Phenotypic Perspective on Mammalian Oxygen Sensor Candidates

Ann NY Acad Sci 2006 1073: 221-233. [Abstract] [Full Text] [PDF]  

TARANJIT S GUJRAL and LOIS M MULLIGAN

Molecular Implications of RET Mutations for Pheochromocytoma Risk in Multiple Endocrine Neoplasia 2

Ann NY Acad Sci 2006 1073: 234-240. [Abstract] [Full Text] [PDF]  

THANH-TRUC HUYNH, KAREL PACAK, DONA L WONG, W. MARSTON LINEHAN, DAVID S GOLDSTEIN, ABDEL G ELKAHLOUN, PETER J MUNSON, and GRAEME EISENHOFER

Transcriptional Regulation of Phenylethanolamine N-Methyltransferase in Pheochromocytomas from Patients with von Hippel–Lindau Syndrome and Multiple Endocrine Neoplasia Type 2

Ann NY Acad Sci 2006 1073: 241-252. [Abstract] [Full Text] [PDF]  

KAZUMASA ISOBE, SUMIKO NISSATO, ICHIRO TATSUNO, TORU YASHIRO, KAZUHIRO TAKEKOSHI, and YASUSHI KAWAKAMI

Expression of mRNAs for Succinate Dehydrogenase Subunits and Related Genes in Pheochromocytoma

Ann NY Acad Sci 2006 1073: 253-262. [Abstract] [Full Text] [PDF]  

SUSANNAH CLEARY and JACQUELINE K PHILLIPS

The Norepinephrine Transporter and Pheochromocytoma

Ann NY Acad Sci 2006 1073: 263-269. [Abstract] [Full Text] [PDF]  

ZHENG-PEI ZENG, DONG-MEI LIU, HAN-ZHONG LI, XIN-RONG FAN, GUO-QIANG LIU, WEI-GANG YAN, AN-LI TONG, and XIN ZHENG

Expression and Effect of Adrenomedullin in Pheochromocytoma

Ann NY Acad Sci 2006 1073: 270-276. [Abstract] [Full Text] [PDF]  

AN-LI TONG, ZHENG-PEI ZENG, HAN-ZHONG LI, DI YANG, LIN LU, and MING LI

Expression and Effect of Transforming Growth Factor- and Tumor Necrosis Factor- in Human Pheochromocytoma

Ann NY Acad Sci 2006 1073: 277-283. [Abstract] [Full Text] [PDF]  

ZHENG-PEI ZENG, GUO-QIANG LIU, HAN-ZHONG LI, XIN-RONG FAN, DONG-MEI LIU, AN-LI TONG, XIN ZHENG, and CHANG LIU

The Effects of Urotensin-II on Proliferation of Pheochromocytoma Cells and mRNA Expression of Urotensin-II and Its Receptor in Pheochromocytoma Tissues

Ann NY Acad Sci 2006 1073: 284-289. [Abstract] [Full Text] [PDF]  

ABDEL G ELKAHLOUN, JAMES F POWERS, ABRAHAM NYSKA, GRAEME EISENHOFER, and ARTHUR S TISCHLER

Gene Expression Profiling of Rat Pheochromocytoma

Ann NY Acad Sci 2006 1073: 290-299. [Abstract] [Full Text] [PDF]  

SHOICHIRO OHTA, EDWIN W LAI, SHUN'ICHIRO TANIGUCHI, ARTHUR S TISCHLER, SALVATORE ALESCI, and KAREL PACAK

Animal Models of Pheochromocytoma Including NIH Initial Experience

Ann NY Acad Sci 2006 1073: 300-305. [Abstract] [Full Text] [PDF]  

CHRISTIAN G ZIEGLER, FLAVIE SICARD, SIMONE SPERBER, MONIKA EHRHART-BORNSTEIN, STEFAN R BORNSTEIN, and ALEXANDER W KRUG

DHEA Reduces NGF-Mediated Cell Survival in Serum-Deprived PC12 Cells

Ann NY Acad Sci 2006 1073: 306-311. [Abstract] [Full Text] [PDF]  

F SICARD, A.W KRUG, C.G ZIEGLER, S SPERBER, M EHRHART-BORNSTEIN, and S.R BORNSTEIN

Role of DHEA and Growth Factors in Chromaffin Cell Proliferation

Ann NY Acad Sci 2006 1073: 312-316. [Abstract] [Full Text] [PDF]  

JANUSZ PUC, GRZEGORZ PLACHA, BOZENNA WOCIAL, KATRINA PODSYPANINA, RAMON PARSONS, and ZBIGNIEW GACIONG

Analysis of PTEN Mutation in Non-familial Pheochromocytoma

Ann NY Acad Sci 2006 1073: 317-331. [Abstract] [Full Text] [PDF]  

Part IV. Biochemical Diagnosis and Tumor Localization:

ASHLEY GROSSMAN, KAREL PACAK, ANNA SAWKA, JACQUES W. M LENDERS, DEBRA HARLANDER, ROBERT T PEASTON, RODNEY REZNEK, JAMES SISSON, and GRAEME EISENHOFER

Biochemical Diagnosis and Localization of Pheochromocytoma: Can We Reach a Consensus?

Ann NY Acad Sci 2006 1073: 332-347. [Abstract] [Full Text] [PDF]  

STEPHAN PETERSENN, NICOLE UNGER, MARTIN K WALZ, and KLAUS MANN

Diagnostic Value of Biochemical Parameters in the Differential Diagnosis of an Adrenal Mass

Ann NY Acad Sci 2006 1073: 348-357. [Abstract] [Full Text] [PDF]  

TOMAS LENZ, JOACHIM ZORNER, CARL KIRCHMAIER, DANIELE PILLITTERI, KLAUS BADENHOOP, CHRISTINE BARTEL, HELMUT GEIGER, KATRIN HASSELBACHER, ULRICH TUSCHY, JÜRGEN WESTERMANN, and LOTHAR SALEWSKI

Multicenter Study on the Diagnostic Value of a New RIA for the Detection of Free Plasma Metanephrines in the Work-Up for Pheochromocytoma

Ann NY Acad Sci 2006 1073: 358-373. [Abstract] [Full Text] [PDF]  

BARRY L SHULKIN, IOANNIS ILIAS, JAMES C SISSON, and KAREL PACAK

Current Trends in Functional Imaging of Pheochromocytomas and Paragangliomas

Ann NY Acad Sci 2006 1073: 374-382. [Abstract] [Full Text] [PDF]  

LAURENCE AMAR, SÉVERINE PEYRARD, PATRICK ROSSIGNOL, FRANCK ZINZINDOHOUE, ANNE-PAULE GIMENEZ-ROQUEPLO, and PIERRE-FRANÇOIS PLOUIN

Changes in Urinary Total Metanephrine Excretion in Recurrent and Malignant Pheochromocytomas and Secreting Paragangliomas

Ann NY Acad Sci 2006 1073: 383-391. [Abstract] [Full Text] [PDF]  

LUCIA MARTINIOVA, SHOICHIRO OHTA, PETER GUION, DANIEL SCHIMEL, EDWIN W LAI, BRENDA KLAUNBERG, ELAINE JAGODA, and KAREL PACAK

Anatomical and Functional Imaging of Tumors in Animal Models: Focus on Pheochromocytoma

Ann NY Acad Sci 2006 1073: 392-404. [Abstract] [Full Text] [PDF]  

Part V. Management:

MASSIMO MANNELLI

Management and Treatment of Pheochromocytomas and Paragangliomas

Ann NY Acad Sci 2006 1073: 405-416. [Abstract] [Full Text] [PDF]  

ANDREAS MACHENS, MICHAEL BRAUCKHOFF, OLIVER GIMM, and HENNING DRALLE

Risk-Oriented Approach to Hereditary Adrenal Pheochromocytoma

Ann NY Acad Sci 2006 1073: 417-428. [Abstract] [Full Text] [PDF]  

SVANTE JANSSON, AMIR KHORRAM-MANESH, OLA NILSSON, LARS KÖLBY, LARS-ERIK TISELL, BO WÄNGBERG, and HÅKAN AHLMAN

Treatment of Bilateral Pheochromocytoma and Adrenal Medullary Hyperplasia

Ann NY Acad Sci 2006 1073: 429-435. [Abstract] [Full Text] [PDF]  

MORRIS J BROWN, ISLA S MACKENZIE, MICHAEL J ASHBY, KOTTEKKATTU K BALAN, and DEREK S APPLETON

AT₂ Receptor Stimulation May Halt Progression of Pheochromocytoma

Ann NY Acad Sci 2006 1073: 436-443. [Abstract] [Full Text] [PDF]  

AMIR KHORRAM-MANESH, SVANTE JANSSON, BO WÄNGBERG, OLA NILSSON, LARS-ERIK TISELL, and HÅKAN AHLMAN

Mortality Associated with Pheochromocytoma: Increased Risk for Additional Tumors

Ann NY Acad Sci 2006 1073: 444-448. [Abstract] [Full Text] [PDF]  

Part VI. Malignant Pheochromocytoma:

HÅKAN AHLMAN

Malignant Pheochromocytoma: State of the Field with Future Projections

Ann NY Acad Sci 2006 1073: 449-464. [Abstract] [Full Text] [PDF]  

PAUL A FITZGERALD, ROBERT E GOLDSBY, JOHN P HUBERTY, DAVID C PRICE, RANDALL A HAWKINS, JANET J VEATCH, FILEMON DELA CRUZ, THIERRY M JAHAN, CHARLES A LINKER, LLOYD DAMON, and KATHERINE K MATTHAY

Malignant Pheochromocytomas and Paragangliomas: A Phase II Study of Therapy with High-Dose ¹³¹I-Metaiodobenzylguanidine (¹³¹I-MIBG)

Ann NY Acad Sci 2006 1073: 465-490. [Abstract] [Full Text] [PDF]  

LARS KÖLBY, PETER BERNHARDT, VIKTOR JOHANSON, BO WÄNGBERG, ANDREAS MUTH, SVANTE JANSSON, EVA FORSSELL-ARONSSON, OLA NILSSON, and HÅKAN AHLMAN

Can Quantification of VMAT and SSTR Expression Be Helpful for Planning Radionuclide Therapy of Malignant Pheochromocytomas?

Ann NY Acad Sci 2006 1073: 491-497. [Abstract] [Full Text] [PDF]  

EVA FORSSELL-ARONSSON, PETER BERNHARDT, BO WÄNGBERG, LARS KÖLBY, OLA NILSSON, and HÅKAN AHLMAN

Aspects on Radionuclide Therapy in Malignant Pheochromocytomas

Ann NY Acad Sci 2006 1073: 498-504. [Abstract] [Full Text] [PDF]  

JAMES C SISSON, BARRY L SHULKIN, and NAZANENE H ESFANDIARI

Courses of Malignant Pheochromocytoma: Implications for Therapy

Ann NY Acad Sci 2006 1073: 505-511. [Abstract] [Full Text] [PDF]  

BO WÄNGBERG, ANDREAS MUTH, AMIR KHORRAM-MANESH, SVANTE JANSSON, OLA NILSSON, EVA FORSSELL-ARONSSON, LARSERIK TISELL, and HÅKAN AHLMAN

Malignant Pheochromocytoma in a Population-Based Study: Survival and Clinical Results

Ann NY Acad Sci 2006 1073: 512-516. [Abstract] [Full Text] [PDF]  

CHRISTIAN A KOCH, OLIVER GIMM, ALEXANDER O VORTMEYER, HAIFA K AL-ALI, PETER LAMESCH, RUDOLF OTT, REGINE KLUGE, UTA BIERBACH, and ANDREA TANNAPFEL

Does the Expression of c-kit (CD117) in Neuroendocrine Tumors Represent a Target for Therapy?

Ann NY Acad Sci 2006 1073: 517-526. [Abstract] [Full Text] [PDF]  

JOHANN GUILLEMOT, LAURE BARBIER, ERWAN THOUENNON, VIRGINIE VALLET-ERDTMANN, MAITE MONTERO-HADJADJE, HERVE LEFEBVRE, MARC KLEIN, MIHAELA MURESAN, PIERRE-FRANÇOIS PLOUIN, NABIL SEIDAH, HUBERT VAUDRY, YOUSSEF ANOUAR, and LAURENT YON

Expression and Processing of the Neuroendocrine Protein Secretogranin II in Benign and Malignant Pheochromocytomas

Ann NY Acad Sci 2006 1073: 527-532. [Abstract] [Full Text] [PDF]  

YOUSSEF ANOUAR, LAURENT YON, JOHANN GUILLEMOT, ERWAN THOUENNON, LAURE BARBIER, ANNE-PAULE GIMENEZ-ROQUEPLO, JEROME BERTHERAT, HERVE LEFEBVRE, MARC KLEIN, MIHAELA MURESAN, ERIC GROUZMANN, PIERRE-FRANÇOIS PLOUIN, HUBERT VAUDRY, and ABDEL G ELKAHLOUN

Development of Novel Tools for the Diagnosis and Prognosis of Pheochromocytoma Using Peptide Marker Immunoassay and Gene Expression Profiling Approaches

Ann NY Acad Sci 2006 1073: 533-540. [Abstract] [Full Text] [PDF]  

FREDERIEKE M BROUWERS, ABDEL G ELKAHLOUN, PETER J MUNSON, GRAEME EISENHOFER, JENNIFER BARB, W. MARSTON LINEHAN, JACQUES W.M LENDERS, RONALD DE KRIJGER, MASSIMO MANNELLI, ROBERT UDELSMAN, IDRIS T OCAL, BARRY L SHULKIN, STEFAN R BORNSTEIN, JAN BREZA, LUCIA KSINANTOVA, and KAREL PACAK

Gene Expression Profiling of Benign and Malignant Pheochromocytoma

Ann NY Acad Sci 2006 1073: 541-556. [Abstract] [Full Text] [PDF]  

Part VII. Pathology:

ARTHUR S TISCHLER, NORIKO KIMURA, and ANNE MARIE MCNICOL

Pathology of Pheochromocytoma and Extra-adrenal Paraganglioma

Ann NY Acad Sci 2006 1073: 557-570. [Abstract] [Full Text] [PDF]  

OLIVER GIMM, ULF KRAUSE, MICHAEL BRAUCKHOFF, CUONG HOANG-VU, and HENNING DRALLE

Distinct Expression of Galectin-3 in Pheochromocytomas

Ann NY Acad Sci 2006 1073: 571-577. [Abstract] [Full Text] [PDF]  

HOLGER S WILLENBERG, MATTHIAS SCHOTT, WOLFGANG SAEGER, ANNETTE TRIES, WERNER A SCHERBAUM, and STEFAN R BORNSTEIN

Expression of Connexins in Chromaffin Cells of Normal Human Adrenals and in Benign and Malignant Pheochromocytomas

Ann NY Acad Sci 2006 1073: 578-583. [Abstract] [Full Text] [PDF]  

Index of Contributors:

Index of Contributors

Ann NY Acad Sci 2006 1073: 585-588. [PDF]  

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