SURESH I. S. RATTAN and SERIF AKMAN
Preface: Biogerontology: Mechanisms and Interventions
Ann NY Acad Sci 1100: xiii. [Full Text] [PDF]  

LEONARD HAYFLICK
Biological Aging Is No Longer an Unsolved Problem
Ann NY Acad Sci 1100: 1–13. [Abstract] [Full Text] [PDF]  

GEORGE M. MARTIN
Modalities of Gene Action Predicted by the Classical Evolutionary Biological Theory of Aging
Ann NY Acad Sci 1100: 14–20. [Abstract] [Full Text] [PDF]  

CLAUDIO FRANCESCHI, VLADYSLAV BEZRUKOV, HÉLÈNE BLANCHÉ, LARS BOLUND, KAARE CHRISTENSEN, GIOVANNA DE BENEDICTIS, LUCA DEIANA, EFSTHATIOS GONOS, ANTTI HERVONEN, HUANNING YANG, BERNARD JEUNE, TOM B. L. KIRKWOOD, PETER KRISTENSEN, ALBERTA LEON, PIER GIUSEPPE PELICCI, LEENA PELTONEN, MICHEL POULAIN, IRENE MAEVE REA, JOSÉ REMACLE, JEAN MARIE ROBINE, STEFAN SCHREIBER, EWA SIKORA, PIETERNELLA ELINE SLAGBOOM, LIANA SPAZZAFUMO, MARIA ANTONIETTA STAZI, OLIVIER TOUSSAINT, and JAMES W. VAUPEL
Genetics of Healthy Aging in Europe: The EU-Integrated Project GEHA (GEnetics of Healthy Aging)
Ann NY Acad Sci 1100: 21–45. [Abstract] [Full Text] [PDF]  

EUGENE M. G. MILNE
Postponement of Postmenopausal Mortality Acceleration in Low-Mortality Populations
Ann NY Acad Sci 1100: 46–59. [Abstract] [Full Text] [PDF]  

MARIO F. FRAGA, RUBEN AGRELO, and MANEL ESTELLER
Cross-Talk between Aging and Cancer: The Epigenetic Language
Ann NY Acad Sci 1100: 60–74. [Abstract] [Full Text] [PDF]  

JENS KRØLL
Molecular Chaperones and the Epigenetics of Longevity and Cancer Resistance
Ann NY Acad Sci 1100: 75–83. [Abstract] [Full Text] [PDF]  

DAVID VAN BODEGOM, LINDA MAY, HANS J. MEIJ, and RUDI G. J. WESTENDORP
Regulation of Human Life Histories: The Role of the Inflammatory Host Response
Ann NY Acad Sci 1100: 84–97. [Abstract] [Full Text] [PDF]  

ANDRU TOMOIU, ANIS LARBI, CARL FORTIN, GILLES DUPUIS, and TAMAS FULOP, JR
Do Membrane Rafts Contribute to Human Immunosenescence?
Ann NY Acad Sci 1100: 98–110. [Abstract] [Full Text] [PDF]  

SONYA VASTO, EUGENIO MOCCHEGIANI, MARCO MALAVOLTA, IRENE CUPPARI, FLORINDA LISTÌ, DOMENICO NUZZO, VITO DITTA, GIUSEPPINA CANDORE, and CALOGERO CARUSO
Zinc and Inflammatory/Immune Response in Aging
Ann NY Acad Sci 1100: 111–122. [Abstract] [Full Text] [PDF]  

MARIA PAOLA GRIMALDI, SONYA VASTO, CARMELA RITA BALISTRERI, DANIELE DI CARLO, MARCO CARUSO, EGLE INCALCATERRA, DOMENICO LIO, CALOGERO CARUSO, and GIUSEPPINA CANDORE
Genetics of Inflammation in Age-Related Atherosclerosis: Its Relevance to Pharmacogenomics
Ann NY Acad Sci 1100: 123–131. [Abstract] [Full Text] [PDF]  

FLORINDA LISTÌ, CALOGERO CARUSO, CARMELA RITA BALISTRERI, MARIA PAOLA GRIMALDI, MARCO CARUSO, GREGORIO CAIMI, ENRICO HOFFMANN, DOMENICO LIO, and GIUSEPPINA CANDORE
PECAM-1/CD31 in Infarction and Longevity
Ann NY Acad Sci 1100: 132–139. [Abstract] [Full Text] [PDF]  

PETER VAN VLIET, SIMON P. MOOIJAART, ANTON J. M. DE CRAEN, PATRICK C. N. RENSEN, DIANA VAN HEEMST, and RUDI G. J. WESTENDORP
Plasma Levels of Apolipoprotein E and Risk of Stroke in Old Age
Ann NY Acad Sci 1100: 140–147. [Abstract] [Full Text] [PDF]  

SIMON P. MOOIJAART, PETER VAN VLIET, DIANA VAN HEEMST, PATRICK C. N. RENSEN, JIMMY F. P. BERBÉE, JELLE JOLLES, ANTON J. M. DE CRAEN, and RUDI G. J. WESTENDORP
Plasma Levels of Apolipoprotein E and Cognitive Function in Old Age
Ann NY Acad Sci 1100: 148–161. [Abstract] [Full Text] [PDF]  

CARMELA RITA BALISTRERI, CALOGERO CARUSO, MARIA PAOLA GRIMALDI, FLORINDA LISTÌ, SONYA VASTO, VALENTINA ORLANDO, ANNA MARIA CAMPAGNA, DOMENICO LIO, and GIUSEPPINA CANDORE
CCR5 Receptor: Biologic and Genetic Implications in Age-Related Diseases
Ann NY Acad Sci 1100: 162–172. [Abstract] [Full Text] [PDF]  

HULAGU KAPTAN, OMUR KASIMCAN, KUTAY CAKIROGLU, MUSTAFA NECMI ILHAN, and CELAL KILIC
Lumbar Spinal Stenosis in Elderly Patients
Ann NY Acad Sci 1100: 173–178. [Abstract] [Full Text] [PDF]  

HULYA CICEK, SIBEL BAYIL, YASEMIN ZER, AHMET CELIK, and ICLAL GEYIKLI
Comparison of Lipoprotein(a) Levels between Elderly and Middle-Aged Men with Coronary Artery Disease
Ann NY Acad Sci 1100: 179–184. [Abstract] [Full Text] [PDF]  

ISMAIL KURT, DILEK ABASLI, MURAT CIHAN, MUHITTIN A. SERDAR, ABDULLAH OLGUN, ERCAN SARUHAN, and M. KEMAL ERBIL
Chitotriosidase Levels in Healthy Elderly Subjects
Ann NY Acad Sci 1100: 185–188. [Abstract] [Full Text] [PDF]  

S. TROMPET, D. PONS, A. J. M. DE CRAEN, P. SLAGBOOM, J. SHEPHERD, G. J. BLAUW, M. B. MURPHY, S. M. COBBE, E.L.E.M. BOLLEN, B. M. BUCKLEY, I. FORD, M. HYLAND, A. GAW, P. W. MACFARLANE, C. J. PACKARD, J. NORRIE, I. J. PERRY, D. J. STOTT, B. J. SWEENEY, C. TWOMEY, R. G. J. WESTENDORP, J. W. JUKEMA ON BEHALF OF THE PROSPER GROUP
Genetic Variation in the Interleukin-10 Gene Promoter and Risk of Coronary and Cerebrovascular Events: The PROSPER Study
Ann NY Acad Sci 1100: 189–198. [Abstract] [Full Text] [PDF]  

ZUHAL YILDIRIM, N. IREM UÇGUN, NEDRET KILIÇ, E. GÜRSEL, and AYLIN SEPICI-DINÇEL
Antioxidant Enzymes and Diabetic Retinopathy
Ann NY Acad Sci 1100: 199–206. [Abstract] [Full Text] [PDF]  

ZUHAL YILDIRIM, N. IREM UÇGUN, NEDRET KILIÇ, E. GÜRSEL, and AYLIN SEPICI-DINÇEL
Pseudoexfoliation Syndrome and Trace Elements
Ann NY Acad Sci 1100: 207–212. [Abstract] [Full Text] [PDF]  

NIL IREM UÇGUN, ZUHAL YILDIRIM, NEDRET KILIÇ, and EMIN GÜRSEL
The Importance of Serum Lipids in Exudative Diabetic Macular Edema in Type 2 Diabetic Patients
Ann NY Acad Sci 1100: 213–217. [Abstract] [Full Text] [PDF]  

ERCAN SARUHAN, ABDULLAH OLGUN, KAMILE ÖZTÜRK, SERIF AKMAN, and M. KEMAL ERBIL
Age-Related Paraoxonase Activity Changes in Turkish Population
Ann NY Acad Sci 1100: 218–222. [Abstract] [Full Text] [PDF]  

B. BERÇIK INAL, M. KOLDAS, H. INAL, C. COSKUN, A. GÜMÜS, and Y. DÖVENTAS
Evaluation of Measurement Uncertainty of Glucose in Clinical Chemistry
Ann NY Acad Sci 1100: 223–226. [Abstract] [Full Text] [PDF]  

KIM J. KRISHNAN, LAURA C. GREAVES, AMY K. REEVE, and DOUGLASS M. TURNBULL
Mitochondrial DNA Mutations and Aging
Ann NY Acad Sci 1100: 227–240. [Abstract] [Full Text] [PDF]  

ABDULLAH OLGUN and SERIF AKMAN
Mitochondrial DNA-Deficient Models and Aging
Ann NY Acad Sci 1100: 241–245. [Abstract] [Full Text] [PDF]  

KAMILE ÖZTÜRK, ABDULLAH OLGUN, ERCAN SARUHAN, AYDAN ERGEN, SERIF AKMAN, and M. KEMAL ERBIL
Mitochondrial DNA Alterations in Aging
Ann NY Acad Sci 1100: 246–249. [Abstract] [Full Text] [PDF]  

ISHITA S. MEHTA, MARTIN FIGGITT, CRAIG S. CLEMENTS, IAN R. KILL, and JOANNA M. BRIDGER
Alterations to Nuclear Architecture and Genome Behavior in Senescent Cells
Ann NY Acad Sci 1100: 250–263. [Abstract] [Full Text] [PDF]  

HUIYUN LIANG, YIDONG BAI, YOUFEN LI, ARLAN RICHARDSON, and WALTER F. WARD
PGC-1-Induced Mitochondrial Alterations in 3T3 Fibroblast Cells
Ann NY Acad Sci 1100: 264–279. [Abstract] [Full Text] [PDF]  

ANNE-LAURE BULTEAU, MARIELLE MOREAU, CARINE NIZARD, and BERTRAND FRIGUET
Proteasome and Photoaging: The Effects of UV Irradiation
Ann NY Acad Sci 1100: 280–290. [Abstract] [Full Text] [PDF]  

NORBERT A. DENCHER, MONIKA FRENZEL, NICOLE H. REIFSCHNEIDER, MICHIRU SUGAWA, and FRANK KRAUSE
Proteome Alterations in Rat Mitochondria Caused by Aging
Ann NY Acad Sci 1100: 291–298. [Abstract] [Full Text] [PDF]  

ANDREANA N. PENA and OLIVIA M. PEREIRA-SMITH
The Role of the MORF/MRG Family of Genes in Cell Growth, Differentiation, DNA Repair, and Thereby Aging
Ann NY Acad Sci 1100: 299–305. [Abstract] [Full Text] [PDF]  

TOMOKO YAGUCHI, SATOSHI AIDA, SUNIL C. KAUL, and RENU WADHWA
Involvement of Mortalin in Cellular Senescence from the Perspective of its Mitochondrial Import, Chaperone, and Oxidative Stress Management Functions
Ann NY Acad Sci 1100: 306–311. [Abstract] [Full Text] [PDF]  

HASAN M. KAMRUL, RENU WADHWA, and SUNIL C. KAUL
CARF Binds to Three Members (ARF, p53, and HDM2) of the p53 Tumor-Suppressor Pathway
Ann NY Acad Sci 1100: 312–315. [Abstract] [Full Text] [PDF]  

STEPHANIE ZDANOV, FLORENCE DEBACQ-CHAINIAUX, and OLIVIER TOUSSAINT
Knocking Down p53 with siRNA Does Not Affect the Overexpression of p21^WAF-1 after Exposure of IMR-90 hTERT Fibroblasts to a Sublethal Concentration of H₂O₂ Leading to Premature Senescence
Ann NY Acad Sci 1100: 316–322. [Abstract] [Full Text] [PDF]  

ANDREA B. MAIER, RUDI G. J. WESTENDORP, and DIANA VAN HEEMST
-Galactosidase Activity as a Biomarker of Replicative Senescence during the Course of Human Fibroblast Cultures
Ann NY Acad Sci 1100: 323–332. [Abstract] [Full Text] [PDF]  

ZHENYU JU, AAHELI ROY CHOUDHURY, and K. LENHARD RUDOLPH
A Dual Role of p21 in Stem Cell Aging
Ann NY Acad Sci 1100: 333–344. [Abstract] [Full Text] [PDF]  

S. BECCAFICO, C. PUGLIELLI, T. PIETRANGELO, R. BELLOMO, G. FANÒ, and S. FULLE
Age-Dependent Effects on Functional Aspects in Human Satellite Cells
Ann NY Acad Sci 1100: 345–352. [Abstract] [Full Text] [PDF]  

OGUZHAN YILDIZ
Vascular Smooth Muscle and Endothelial Functions in Aging
Ann NY Acad Sci 1100: 353–360. [Abstract] [Full Text] [PDF]  

KALLIOPE E. SEKERI-PATARYAS and THOMAE G. SOURLINGAS
The Differentiation-Associated Linker Histone, H1.0, during the in Vitro Aging and Senescence of Human Diploid Fibroblasts
Ann NY Acad Sci 1100: 361–367. [Abstract] [Full Text] [PDF]  

ZEENIA KAUL, TOMOKO YAGUCHI, HIROSHI X. CHIURA, SUNIL C. KAUL, and RENU WADHWA
Quantum Dot-Based Mortalin Staining as a Visual Assay for Detection of Induced Senescence in Cancer Cells
Ann NY Acad Sci 1100: 368–372. [Abstract] [Full Text] [PDF]  

SYED IBRAHIM RIZVI and PAWAN KUMAR MAURYA
Markers of Oxidative Stress in Erythrocytes during Aging in Humans
Ann NY Acad Sci 1100: 373–382. [Abstract] [Full Text] [PDF]  

AHMET KOC and VADIM N. GLADYSHEV
Methionine Sulfoxide Reduction and the Aging Process
Ann NY Acad Sci 1100: 383–386. [Abstract] [Full Text] [PDF]  

TEIMURAZ LEZHAVA and TINA JOKHADZE
Activation of Pericentromeric and Telomeric Heterochromatin in Cultured Lymphocytes from Old Individuals
Ann NY Acad Sci 1100: 387–399. [Abstract] [Full Text] [PDF]  

ABDULLAH OLGUN, KAMILE ÖZTÜRK, SELDA BAYIR, SERIF AKMAN, and M. KEMAL ERBIL
Deuteronation and Aging
Ann NY Acad Sci 1100: 400–403. [Abstract] [Full Text] [PDF]  

CIHAN COSKUN, ALEV KURAL, YASEMIN DÖVENTAS, MACIT KOLDAS, HÜMEYRA ÖZTURK, BERRIN BERÇIK INAL, and ALPER GÜMÜS
Hemodialysis and Protein Oxidation Products
Ann NY Acad Sci 1100: 404–408. [Abstract] [Full Text] [PDF]  

AUBREY D. N. J. DE GREY
The Natural Biogerontology Portfolio: "Defeating Aging" as a Multi-stage Ultra-grand Challenge
Ann NY Acad Sci 1100: 409–423. [Abstract] [Full Text] [PDF]  

SURESH I. S. RATTAN and REHAB E. ALI
Hormetic Prevention of Molecular Damage during Cellular Aging of Human Skin Fibroblasts and Keratinocytes
Ann NY Acad Sci 1100: 424–430. [Abstract] [Full Text] [PDF]  

SATARO GOTO, RYOYA TAKAHASHI, ZSOLT RADAK, and RAMESH SHARMA
Beneficial Biochemical Outcomes of Late-Onset Dietary Restriction in Rodents
Ann NY Acad Sci 1100: 431–441. [Abstract] [Full Text] [PDF]  

ISABELLE LENAERTS, SYLVIE VAN EYGEN, and JACQUES VAN FLETEREN
Adult-Limited Dietary Restriction Slows Gompertzian Aging in Caenorhabditis elegans
Ann NY Acad Sci 1100: 442–448. [Abstract] [Full Text] [PDF]  

DIMITRIS KLETSAS, HARRIS PRATSINIS, VASSILIKI GIONI, KONSTANTINOS PILICHOS, ANDREAS M. YIACOUMETTIS, and STYLIANOS TSAGARAKIS
Prior Chronic in Vivo Glucocorticoid Excess Leads to an Anabolic Phenotype and an Extension of Cellular Life Span of Skin Fibroblasts in Vitro
Ann NY Acad Sci 1100: 449–454. [Abstract] [Full Text] [PDF]  

TERENCE DAVIS, FIONA S. WYLLIE, MICHAL J. ROKICKI, MARK C. BAGLEY, and DAVID KIPLING
The Role of Cellular Senescence in Werner Syndrome: Toward Therapeutic Intervention in Human Premature Aging
Ann NY Acad Sci 1100: 455–469. [Abstract] [Full Text] [PDF]  

JAMES A. JOSEPH, BARBARA SHUKITT-HALE, and FRANCIS C. LAU
Fruit Polyphenols and Their Effects on Neuronal Signaling and Behavior in Senescence
Ann NY Acad Sci 1100: 470–485. [Abstract] [Full Text] [PDF]  

SOON YEW TANG, JAN GRUBER, KIM PING WONG, and BARRY HALLIWELL
Psoralea corylifolia L. Inhibits Mitochondrial Complex I and Proteasome Activities in SH-SY5Y Cells
Ann NY Acad Sci 1100: 486–496. [Abstract] [Full Text] [PDF]  

ISABEL BAEZA, NURIA M. DE CASTRO, CARMEN ALVARADO, PEDRO ÁLVAREZ, LORENA ARRANZ, JULIÁN BAYÓN, and MÓNICA DE LA FUENTE
Improvement of Immune Cell Functions in Aged Mice Treated for Five Weeks with Soybean Isoflavones
Ann NY Acad Sci 1100: 497–504. [Abstract] [Full Text] [PDF]  

ERCAN SELCUK UNLU and AHMET KOC
Effects of Deleting Mitochondrial Antioxidant Genes on Life Span
Ann NY Acad Sci 1100: 505–509. [Abstract] [Full Text] [PDF]  

FERIHAN CETIN and SIBEL DINCER
The Effect of Intrahippocampal Beta Amyloid (1-42) Peptide Injection on Oxidant and Antioxidant Status in Rat Brain
Ann NY Acad Sci 1100: 510–517. [Abstract] [Full Text] [PDF]  

HENRIK SEJERSEN and SURESH I. S. RATTAN
Glyoxal-Induced Premature Senescence in Human Fibroblasts
Ann NY Acad Sci 1100: 518–523. [Abstract] [Full Text] [PDF]  

ULRICH BERGE, JULIANE BEHRENS, and SURESH I. S. RATTAN
Sugar-Induced Premature Aging and Altered Differentiation in Human Epidermal Keratinocytes
Ann NY Acad Sci 1100: 524–529. [Abstract] [Full Text] [PDF]  

JAN GRUBER, SOON YEW TANG, and BARRY HALLIWELL
Evidence for a Trade-Off between Survival and Fitness Caused by Resveratrol Treatment of Caenorhabditis elegans
Ann NY Acad Sci 1100: 530–542. [Abstract] [Full Text] [PDF]  

CLAUSTRO ZAMBRANA, EVA M. MARCO, LORENA ARRANZ, NURIA M. de CASTRO, MARIA PAZ VIVEROS, and MÓNICA DE LA FUENTE
Influence of Aging and Enriched Environment on Motor Activity and Emotional Responses in Mice
Ann NY Acad Sci 1100: 543–552. [Abstract] [Full Text] [PDF]  

ZUHAL YILDIRIM, NEDRET KILIÇ, ÇIGDEM OZER, AYDAN BABUL, GULNUR TAKE, and DENIZ ERDOGAN
Effects of Taurine in Cellular Responses to Oxidative Stress in Young and Middle-Aged Rat Liver
Ann NY Acad Sci 1100: 553–561. [Abstract] [Full Text] [PDF]