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IMIDAZOLINE RECEPTORS AND THEIR ENDOGENOUS LIGANDS: CURRENT CONCEPTS AND THERAPEUTIC POTENTIAL

Volume 881 published June 1999
Editors:
Manfred Göthert
Gerhard J. Molderings
Donald J. Reis
Index of Authors
Contents
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To see an article, click its [Full Text] or [PDF] link. To review many abstracts, check the boxes to the left of the titles you want, and click the 'Get All Checked Abstract(s)' button. To see one abstract at a time, click its [Abstract] link.

MANFRED GÖTHERT, GERHARD J. MOLDERINGS, and DONALD J. REIS
Preface
Ann NY Acad Sci 1999 881: xiii. [Full Text] [PDF]  

Part I. Molecular and Cell Biology:
JOHN E. PILETZ, JULIA CAY JONES, HE ZHU, OSAMA BISHARA, and PAUL ERNSBERGER
Imidazoline Receptor Antisera-Selected cDNA Clone and mRNA Distribution
Ann NY Acad Sci 1999 881: 1-7. [Abstract] [Full Text] [PDF]  

PABLO V. ESCRIBÁ, ANDRÉS OZAITA, and JESÚS A. GARCÍA-SEVILLA
Pharmacologic Characterization of Imidazoline Receptor Proteins Identified by Immunologic Techniques and Other Methods
Ann NY Acad Sci 1999 881: 8-25. [Abstract] [Full Text] [PDF]  

RITA RADDATZ, SANDRA L. SAVIC, and S. M. LANIER
Imidazoline Binding Domains on MAO-B: Localization and Accessibility
Ann NY Acad Sci 1999 881: 26-31. [Abstract] [Full Text] [PDF]  

A. REMAURY, C. ORDENER, J. SHIH, and A. PARINI
Relationship between I2 Imidazoline Binding Sites and Monoamine Oxidase B in Liver
Ann NY Acad Sci 1999 881: 32-34. [Abstract] [Full Text] [PDF]  

PAUL ERNSBERGER
The I1-Imidazoline Receptor and Its Cellular Signaling Pathways
Ann NY Acad Sci 1999 881: 35-53. [Abstract] [Full Text] [PDF]  

H. GRENEY, F. HEEMSKERK, C. VONTHRON, C. MAGNIER, P. BOUSQUET, and M. DONTENWILL
Coexpression of Imidazoline Receptors and Alpha2-Adrenoceptors in Neuroglial Cell Line NG 108,15
Ann NY Acad Sci 1999 881: 54-58. [Full Text] [PDF]  

C. ORDENER, H. GRENEY, J. DEVEDJIAN, M. DONTENWILL, P. BOUSQUET, and A. PARINI
Transfected Cells Expressing the Three Subtypes of Alpha2-Adrenergic Receptors Lack I1-Imidazoline Binding Sites
Ann NY Acad Sci 1999 881: 59-60. [Full Text] [PDF]  

ANTONIO MIRALLES, ANDRÉS OZAITA, CATALINA RIBAS, and JESÚS A. GARCÍA-SEVILLA
Lack of Effect of Reserpine on Immunoreactive Imidazoline Receptor Proteins in Rat Brain
Ann NY Acad Sci 1999 881: 61-64. [Full Text] [PDF]  

Part II. Endogenous and Novel Exogenous Ligands of Imidazoline Receptors:
DONALD J. REIS and SOUNDARARAJAN REGUNATHAN
Agmatine: An Endogenous Ligand at Imidazoline Receptors Is a Novel Neurotransmitter
Ann NY Acad Sci 1999 881: 65-80. [Abstract] [Full Text] [PDF]  

A. L. HUDSON, R. GOUGH, R. TYACKE, L. LIONE, M. LALIES, J. LEWIS, S. HUSBANDS, P. KNIGHT, F. MURRAY, P. HUTSON, and D. J. NUTT
Novel Selective Compounds for the Investigation of Imidazoline Receptors
Ann NY Acad Sci 1999 881: 81-91. [Abstract] [Full Text] [PDF]  

CHRISTINE A. PARKER, ALAN L. HUDSON, DAVID J. NUTT, MICHAEL P. DILLON, RICHARD M. EGLEN, and JOHN CROSBY
Comparison of Crude Methanolic CDS Extracts from Various Tissues
Ann NY Acad Sci 1999 881: 92-96. [Full Text] [PDF]  

U. SCHÄFER, W. RAASCH, F. QADRI, J. CHUN, and P. DOMINIAK
Effects of Agmatine on the Cardiovascular System of Spontaneously Hypertensive Rats
Ann NY Acad Sci 1999 881: 97-101. [Full Text] [PDF]  

V. BRUBAN, J. FELDMAN, M. DONTENWILL, H. GRENEY, L. BRASILI, M. GIANNELLA, M. PIGINI, and P. BOUSQUET
An Unexpected Central Hypertensive Effect of the New Imidazoline Compound Benazoline
Ann NY Acad Sci 1999 881: 102-105. [Full Text] [PDF]  

EWA KRZYSTANEK, MAREK KRZYSTANEK, FRANCISZEK SACZEWSKI, TOMASZ DEBOWSKI, and HANNA TRZECIAK
Structure of New Imidazoline Derivatives and Their Cardiovascular Effect in Rats
Ann NY Acad Sci 1999 881: 106-109. [Full Text] [PDF]  

DOROTHY H. WOOD, JAMES EDWIN HALL, BEATE G. ROSE, DAVID W. BOYKIN, and RICHARD R. TIDWELL
Pentamidine Is a Potent Inhibitor of [3H]Idazoxan Binding to Imidazoline I2 Receptors
Ann NY Acad Sci 1999 881: 110-113. [Full Text] [PDF]  

M. D. LALIES, A. HIBELL, A. L. HUDSON, and D. J. NUTT
Inhibition of Central Monoamine Oxidase by Imidazoline2 Site-Selective Ligands
Ann NY Acad Sci 1999 881: 114-117. [Full Text] [PDF]  

M. PIGINI, P. BOUSQUET, L. BRASILI, A. CARRIERI, M. DONTENWILL, F. GENTILI, M. GIANNELLA, F. LEONETTI, A. PIERGENTILI, W. QUAGLIA, and A. CAROTTI
Binding of Tracizolines to the Imidazoline Receptor: Role of Lipophilicity in Quantitative Structure-Activity Relationship Models
Ann NY Acad Sci 1999 881: 118-122. [Full Text] [PDF]  

Part III. Identification, Distribution, and Pharmacology of Imidazoline Receptor Types and Subtypes:
M. DONTENWILL, C. VONTHRON, H. GRENEY, C. MAGNIER, F. HEEMSKERK, and P. BOUSQUET
Identification of Human I1 Receptors and Their Relationship to {alpha}2-Adrenoceptors
Ann NY Acad Sci 1999 881: 123-134. [Abstract] [Full Text] [PDF]  

GEORGES VAUQUELIN, JEAN-PAUL DE BACKER, PHILIPPE LADURE, and ANJA FLAMEZ
Identification of I1 and I2 Imidazoline Receptors in Striatum Membranes from Different Species
Ann NY Acad Sci 1999 881: 135-143. [Abstract] [Full Text] [PDF]  

GABRIEL OLMOS, REGINA ALEMANY, M. ASSUMPCIÓ BORONAT, and JESÚS A. GARCÍA-SEVILLA
Pharmacologic and Molecular Discrimination of I2-Imidazoline Receptor Subtypes
Ann NY Acad Sci 1999 881: 144-160. [Abstract] [Full Text] [PDF]  

P. R. KING, A. L GUNDLACH, and W. J. LOUIS
Identification of Imidazoline-Receptor Binding Sites in Cortex and Medulla of the Bovine Adrenal Gland: Colocalization with MAO-A and MAO-B
Ann NY Acad Sci 1999 881: 161-170. [Abstract] [Full Text] [PDF]  

M. GÖTHERT, M. BRÜSS, H. BÖNISCH, and G. J. MOLDERINGS
Presynaptic Imidazoline Receptors: New Developments in Characterization and Classification
Ann NY Acad Sci 1999 881: 171-184. [Abstract] [Full Text] [PDF]  

F. M. J. HEEMSKERK, M. DONTENWILL, H. GRENEY, C. VONTHRON, and P. BOUSQUET
Evidence for Presynaptic High Affinity Imidazoline-Specific Binding Sites in the Bovine Brainstem
Ann NY Acad Sci 1999 881: 185-188. [Full Text] [PDF]  

T. C. DANBURY, B. RUBAN, A. L. HUDSON, A. E. WATERMAN-PEARSON, and S. C. KESTIN
Imidazoline (I2) Binding Sites in Chicken Brain
Ann NY Acad Sci 1999 881: 189-192. [Full Text] [PDF]  

M. I. STEINBERG, S. A. WIEST, R. T. PICKARD, K. CHEN, and J. C. SHIH
Binding of the Imidazoline Ligand3H-2-Benzofuranyl-2-Imidazoline (BFI) to Human Brain and Platelets: Potentiation by Tranylcypromine and Role of MAO Isoforms
Ann NY Acad Sci 1999 881: 193-198. [Full Text] [PDF]  

ISABEL ULIBARRI, JOHANKA SOTO, JAVIER RUIZ, JAVIER BALLESTEROS, JOSÉ V. JAÚREGUI, and J. JAVIER MEANA
I
Ann NY Acad Sci 1999 881: 199-202. [Full Text] [PDF]  

FERNANDO BARTUREN, PERE VENTAYOL, ANDRÉS OZAITA, P. V. ESCRIBÁ, J. JAVIER MEANA, and JESÚS A. GARCÍA-SEVILLA
Densities of I2-Imidazoline Receptors, Imidazoline Receptor Proteins, and MAO-B Sites in Human Gliomas and Pituitary Adenomas
Ann NY Acad Sci 1999 881: 203-207. [Full Text] [PDF]  

ROBIN J. TYACKE, DAVID J. NUTT, and ALAN L. HUDSON
Autoradiography of I2 Receptors in Frog Brain
Ann NY Acad Sci 1999 881: 208-211. [Full Text] [PDF]  

A. L. HUDSON, S. LUSCOMBE, R. E. GOUGH, D. J. NUTT, and R. J. TYACKE
Endogenous Indoleamines Demonstrate Moderate Affinity for I2 Binding Sites
Ann NY Acad Sci 1999 881: 212-216. [Full Text] [PDF]  

Part IV. Effects of Imidazolines on Pancreatic B Cells:
NOEL G. MORGAN, SUE L. F. CHAN, MIRNA MOURTADA, LARA K. MONKS, and CHRISTOPHER A. RAMSDEN
Imidazolines and Pancreatic Hormone Secretion
Ann NY Acad Sci 1999 881: 217-228. [Abstract] [Full Text] [PDF]  

I. RUSTENBECK, M. KÖPP, P. RATZKA, L. LEUPOLT, and A. HASSELBLATT
Imidazolines and the Pancreatic B-Cell: Actions and Binding Sites
Ann NY Acad Sci 1999 881: 229-240. [Abstract] [Full Text] [PDF]  

S. V. ZAITSEV, A. M. EFANOV, A. RAAP, I. B. EFANOVA, J. SCHLOOS, B. STECKEL-HAMANN, O. LARSSON, C.-G. ÖSTENSON, P.-O. BERGGREN, H.-J. MEST, and S. EFENDIC
Different Modes of Action of the Imidazoline Compound RX871024 in Pancreatic ß-Cells: Blocking of K
Ann NY Acad Sci 1999 881: 241-252. [Abstract] [Full Text] [PDF]  

Part V. Central Sympathoinhibition by Imidazolines:
BELA SZABO, CHRISTINA BOCK, ULRICH NORDHEIM, and NATHALIE NIEDERHOFFER
Mechanism of the Sympathoinhibition Produced by the Clonidine-Like Drugs Rilmenidine and Moxonidine
Ann NY Acad Sci 1999 881: 253-264. [Full Text] [PDF]  

L. HEIN, L. E. LIMBIRD, R. M. EGLEN, and B. K. KOBILKA
Gene Substitution/Knockout to Delineate the Role of {alpha}2-Adrenoceptor Subtypes in Mediating Central Effects of Catecholamines and Imidazolines
Ann NY Acad Sci 1999 881: 265-271. [Abstract] [Full Text] [PDF]  

P. BOUSQUET, V. BRUBAN, S. SCHANN, H. GRENEY, J. D. EHRHARDT, M. DONTENWILL, and J. FELDMAN
Participation of Imidazoline Receptors and Alpha2--Adrenoceptors in the Central Hypotensive Effects of Imidazoline-Like Drugs
Ann NY Acad Sci 1999 881: 272-278. [Abstract] [Full Text] [PDF]  

GEOFFREY A. HEAD
Central Imidazoline- and {alpha}2-Receptors Involved in the Cardiovascular Actions of Centrally Acting Antihypertensive Agents
Ann NY Acad Sci 1999 881: 279-286. [Abstract] [Full Text] [PDF]  

Q.-M. ZHU, J. D. LESNICK, J. R. JASPER, S. J. MacLENNAN, M. P. DILLON, R. M. EGLEN, and D. R. BLUE, JR.
{alpha}2A-Adrenoceptors, Not I1-Imidazoline Receptors, Mediate the Hypotensive Effects of Rilmenidine and Moxonidine in Conscious Mice: In Vivo and In Vitro Studies
Ann NY Acad Sci 1999 881: 287-289. [Full Text] [PDF]  

D. RICCI and C. A. TAIRA
Importance of Imidazoline Receptors in the Cardiovascular Responses of Clonidine in Sinoaortic Denervated Rats
Ann NY Acad Sci 1999 881: 290-294. [Full Text] [PDF]  

OLEG S. MEDVEDEV, OKSANA R. KUNDUZOVA, ARKADY N. MURASHEV, and NATALYA A. MEDVEDEVA
Influence of Sinoaortic Barodenervation on the Hypotensive Effects of Imidazoline-Like Drugs in Stroke-Prone Spontaneously Hypertensive Rats
Ann NY Acad Sci 1999 881: 295-299. [Full Text] [PDF]  

G. A. HEAD, C. K. S. CHAN, H. ZHU, and J. E. PILETZ
Dissociation of the Effects of Intramedullary Monoamine Neurotoxins on the Hypotensive Action of Moxonidine and on Immunodetected Imidazoline and {alpha}2-Receptor Proteins
Ann NY Acad Sci 1999 881: 300. [Full Text] [PDF]  

Part VI. Targets and Functional Role of Imidazolines Besides Central Sympathoinhibition:
IAN F. MUSGRAVE and RICHARD A. HUGHES
Novel Targets and Techniques in Imidazoline Receptor Research
Ann NY Acad Sci 1999 881: 301-312. [Abstract] [Full Text] [PDF]  

W. RAASCH, H. MUHLE, and P. DOMINIAK
Modulation of MAO Activity by Imidazoline and Guanidine Derivatives
Ann NY Acad Sci 1999 881: 313-331. [Abstract] [Full Text] [PDF]  

G. J. MOLDERINGS, M. BURIAN, S. MENZEL, K. DONECKER, J. HOMANN, M. NILIUS, and M. GÖTHERT
Imidazoline Recognition Sites and Stomach Function
Ann NY Acad Sci 1999 881: 332-343. [Abstract] [Full Text] [PDF]  

DONALD D. SMYTH and S. BRIAN PENNER
Peripheral and Central Imidazoline Receptor-Mediated Natriuresis in the Rat
Ann NY Acad Sci 1999 881: 344-357. [Full Text] [PDF]  

S. ESTEBAN, A. SASTRE-COLL, and J. A. GARCÍA-SEVILLA
Effects of Imidazoline Drugs on Tyrosine and Tryptophan Hydroxylase Activity in Rat Brain in Vivo
Ann NY Acad Sci 1999 881: 358. [Full Text] [PDF]  

M. ASSUMPCIÓ BORONAT, GABRIEL OLMOS, and JESÚS A. GARCÍA-SEVILLA
Attenuation of Tolerance to Opioid-Induced Antinociception by Idazoxan and Other I2-Ligands
Ann NY Acad Sci 1999 881: 359-363. [Full Text] [PDF]  

A. SASTRE-COLL, S. ESTEBAN, and J. A. GARCÍA-SEVILLA
Effects of 2-(2-Benzofuranyl)-2-Imidazoline (2-BFI) on Dopamine Synthesis in Rat Striatum in Vivo
Ann NY Acad Sci 1999 881: 364. [Full Text] [PDF]  

LUISA UGEDO, JOSEBA PINEDA, RAÚL MARTÍN-RUIZ, JOSÉ ANGEL RUIZ-ORTEGA, and FRANCESC ARTIGAS
Imidazoline-Induced Inhibition of Firing Rate of 5-HT Neurons in Rat Dorsal Raphe by Modulation of Extracellular 5-HT Levels
Ann NY Acad Sci 1999 881: 365-368. [Full Text] [PDF]  

M. F. JETT, L. R. HEDLEY, M. P. DILLON, R. M. EGLEN, and J. C. HUNTER
Behavioral Effects of RS-45041-190, a Selective I2 Imidazoline Ligand, in Rats
Ann NY Acad Sci 1999 881: 369-371. [Full Text] [PDF]  

MUSA A. HAXHIU, ISMAIL A. DRESHAJ, CHRISTOPHER B. McFADDEN, BERNADETTE O. EROKWU, and PAUL ERNSBERGER
Moxonidine Acting Centrally Inhibits Airway Reflex Responses
Ann NY Acad Sci 1999 881: 372-382. [Abstract] [Full Text] [PDF]  

JOACHIM GREVEN and BRIGITTE V. BRONEWSKI-SCHWARZER
Localization of the Diuretic Effect of Moxonidine in the Nephron by Micropuncture Experiments in Anesthetized Rats
Ann NY Acad Sci 1999 881: 383-384. [Full Text] [PDF]  

SUHAYLA MUKADDAM-DAHER and JOLANTA GUTKOWSKA
The Renal Actions of Moxonidine Are Mediated by Atrial Natriuretic Peptide and Involve the Opioid Receptors
Ann NY Acad Sci 1999 881: 385-387. [Full Text] [PDF]  

MILLER J. OGIDIGBEN, T. C. CHU, and D. E. POTTER
Peripheral and Central Effects of Naphazoline on Ocular Hydrodynamics: Involvement of Imidazoline Receptors, ANP, and Gi Proteins
Ann NY Acad Sci 1999 881: 388-391. [Full Text] [PDF]  

Part VII. Pathophysiologic and Therapeutic Relevance:
JESÚS A. GARCÍA-SEVILLA, PABLO V. ESCRIBÁ, and JOSÉ GUIMÓN
Imidazoline Receptors and Human Brain Disorders
Ann NY Acad Sci 1999 881: 392-409. [Abstract] [Full Text] [PDF]  

S. REGUNATHAN, D. L. FEINSTEIN, and D. J. REIS
Anti-Proliferative and Anti-Inflammatory Actions of Imidazoline Agents: Are Imidazoline Receptors Involved?
Ann NY Acad Sci 1999 881: 410-419. [Abstract] [Full Text] [PDF]  

P. A. VAN ZWIETEN and S. L. M. PETERS
Central I1-Imidazoline Receptors As Targets of Centrally Acting Antihypertensive Drugs: Clinical Pharmacology of Moxonidine and Rilmenidine
Ann NY Acad Sci 1999 881: 420-429. [Abstract] [Full Text] [PDF]  

HEINZ RUPP
Excess Catecholamine Syndrome: Pathophysiology and Therapy
Ann NY Acad Sci 1999 881: 430-444. [Abstract] [Full Text] [PDF]  

ANGELOS HALARIS, HE ZHU, YENGZHENG FENG, and JOHN E. PILETZ
Plasma Agmatine and Platelet Imidazoline Receptors in Depression
Ann NY Acad Sci 1999 881: 445-451. [Abstract] [Full Text] [PDF]  

N. DeGREGORIO-ROCASOLANO, G. OLMOS, T. GASULL, M. A. BORONAT, R. TRULLAS, and J. A. GARCÍA-SEVILLA
Protection by Imidazol(ine) Compounds of l-Glutamate Neurotoxicity Through NMDA Receptor Blockade
Ann NY Acad Sci 1999 881: 452. [Full Text] [PDF]  

To see an article, click its [Full Text] or [PDF] link. To review many abstracts, check the boxes to the left of the titles you want, and click the 'Get All Checked Abstract(s)' button. To see one abstract at a time, click its [Abstract] link.

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