ANNALS ONLINE -- Table of Contents (November 1999, 893)

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JOHN P. BLASS: Preface; Ann NY Acad Sci 1999 893: xi. [Full Text]

Part I. Fundamental Aspects of Energy Metabolism and Free Radicals:

DAVID G. NICHOLLS, SAMANTHA L. BUDD, ROGER F. CASTILHO, and MANUS W. WARD: Glutamate Excitotoxicity and Neuronal Energy Metabolism; Ann NY Acad Sci 1999 893: 1-12. [Abstract] [Full Text] [PDF]

IRWIN FRIDOVICH: Fundamental Aspects of Reactive Oxygen Species, or What's the Matter with Oxygen?; Ann NY Acad Sci 1999 893: 13-18. [Abstract] [Full Text] [PDF]

Part II. Mitochondrial Calcium Metabolism and the Permeability Transition:

ANNE N. MURPHY: Ca²⁺-Mediated Mitochondrial Dysfunction and the Protective Effects of Bcl-2; Ann NY Acad Sci 1999 893: 19-32. [Abstract] [Full Text] [PDF]

IAN J. REYNOLDS: Mitochondrial Membrane Potential and the Permeability Transition in Excitotoxicity; Ann NY Acad Sci 1999 893: 33-41. [Abstract] [Full Text] [PDF]

Part III. Abnormalities in mtDNA and gDNAs:

JOHN M. SHOFFNER: Oxidative Phosphorylation Disease Diagnosis; Ann NY Acad Sci 1999 893: 42. [Abstract] [Full Text] [PDF]

KWAN-FU REX SHEU and JOHN P. BLASS: The ${alpha}$ -Ketoglutarate Dehydrogenase Complex; Ann NY Acad Sci 1999 893: 61-78. [Abstract] [Full Text] [PDF]

Part IV. Experimental Models of Human Diseases:

GARY E. GIBSON, LARRY C. H. PARK, HUI ZHANG, SANDRO SORBI, and NOEL Y. CALINGASAN: Oxidative Stress and a Key Metabolic Enzyme in Alzheimer Brains, Cultured Cells, and an Animal Model of Chronic Oxidative Deficits; Ann NY Acad Sci 1999 893: 79-94. [Abstract] [Full Text] [PDF]

TING-TING HUANG, ELAINE J. CARLSON, INES RAINERI, ANNE MARIE GILLESPIE, HEATHER KOZY, and CHARLES J. EPSTEIN: The Use of Transgenic and Mutant Mice to Study Oxygen Free Radical Metabolism; Ann NY Acad Sci 1999 893: 95-112. [Abstract] [Full Text] [PDF]

Part V. Physiological Aspects of Energy Metabolism:

RAJ N. KALARIA: The Blood-Brain Barrier and Cerebrovascular Pathology in Alzheimer's Disease; Ann NY Acad Sci 1999 893: 113-125. [Abstract] [Full Text] [PDF]

LAWRENCE P. REAGAN, ANA MARIA MAGARIÑOS, and BRUCE S. McEWEN: Neurological Changes Induced by Stress in Streptozotocin Diabetic Rats; Ann NY Acad Sci 1999 893: 126-137. [Abstract] [Full Text] [PDF]

Part VI. Alzheimer's Disease:

STANLEY I. RAPOPORT: Functional Brain Imaging in the Resting State and during Activation in Alzheimer's Disease: Implications for Disease Mechanisms Involving Oxidative Phosphorylation; Ann NY Acad Sci 1999 893: 138-153. [Abstract] [Full Text] [PDF]

MARK P. MATTSON, WARD A. PEDERSEN, WENZHEN DUAN, CARSTEN CULMSEE, and SIMONETTA CAMANDOLA: Cellular and Molecular Mechanisms Underlying Perturbed Energy Metabolism and Neuronal Degeneration in Alzheimer's and Parkinson's Diseases; Ann NY Acad Sci 1999 893: 154-175. [Abstract] [Full Text] [PDF]

SOUMITRA S. GHOSH, RUSSELL H. SWERDLOW, SCOTT W. MILLER, BRINA SHEEMAN, W. DAVIS PARKER, JR., and ROBERT E. DAVIS: Use of Cytoplasmic Hybrid Cell Lines for Elucidating the Role of Mitochondrial Dysfunction in Alzheimer's Disease and Parkinson's Disease; Ann NY Acad Sci 1999 893: 176-191. [Abstract] [Full Text] [PDF]

Part VII. Huntington's Disease:

YOSHITAKA NAGAI, OSAMU ONODERA, WARREN J. STRITTMATTER, and JAMES R. BURKE: Polyglutamine Domain Proteins with Expanded Repeats Bind Neurofilament, Altering the Neurofilament Network; Ann NY Acad Sci 1999 893: 192-201. [Abstract] [Full Text] [PDF]

THOMAS GRÜNEWALD and M. FLINT BEAL: Bioenergetics in Huntington's Disease; Ann NY Acad Sci 1999 893: 203-213. [Abstract] [Full Text] [PDF]

Part VIII. Cerebrovascular Disease:

B. G. JENKINS, Y. I. CHEN, E. KUESTERMANN, N. M. MAKRIS, T. V. NGUYEN, E. KRAFT, A. L. BROWNELL, H. D. ROSAS, D. N. KENNEDY, B. R. ROSEN, W. J. KOROSHETZ, and M. F. BEAL: An Integrated Strategy for Evaluation of Metabolic and Oxidative Defects in Neurodegenerative Illness Using Magnetic Resonance Techniques; Ann NY Acad Sci 1999 893: 214-242. [Abstract] [Full Text] [PDF]

B. JOY SNIDER, FRANK J. GOTTRON, and DENNIS W. CHOI: Apoptosis and Necrosis in Cerebrovascular Disease; Ann NY Acad Sci 1999 893: 243-253. [Abstract] [Full Text] [PDF]

Part IX. Poster Papers:

ALAIN BOIREAU, PIERRE DUBEDAT, FRANÇOISE BORDIER, MADELEINE COIMBRA, MIREILLE MEUNIER, ASSUNTA IMPERATO, and SALIHA MOUSSAOUI: Effects of Ebselen, a Glutathione Peroxidase Mimic, in Several Models of Mitochondrial Dysfunction; Ann NY Acad Sci 1999 893: 254-257. [Full Text] [PDF]

NICKOLAY BRUSTOVETSKY and JANET M. DUBINSKY: EDTA-Induced Monovalent Fluxes through the Ca²⁺ Uniporter in Brain Mitochondria; Ann NY Acad Sci 1999 893: 258-260. [Full Text] [PDF]

SAMANTHA L. BUDD and STUART A. LIPTON: Signaling Events in NMDA Receptor-Induced Apoptosis in Cerebrocortical Cultures; Ann NY Acad Sci 1999 893: 261-264. [Full Text] [PDF]

D. ALLAN BUTTERFIELD, SERVET M. YATIN, and CHRISTOPHER D. LINK: In Vitro and in vivo Protein Oxidation Induced by Alzheimer's Disease Amyloid ß-Peptide (1-42); Ann NY Acad Sci 1999 893: 265-268. [Full Text] [PDF]

CHRISTOS CHINOPOULOS and VERA ADAM-VIZI: Depolarization of in Situ Mitochondria by Hydrogen Peroxide in Nerve Terminals; Ann NY Acad Sci 1999 893: 269-272. [Full Text] [PDF]

GERALD COHEN and NATASA KESLER: Monoamine Oxidase Inhibits Mitochondrial Respiration; Ann NY Acad Sci 1999 893: 273-278. [Full Text] [PDF]

GERALD A. DIENEL, KENIAN LIU, DAVID POPP, and NANCY F. CRUZ: Enhanced Acetate and Glucose Utilization during Graded Photic Stimulation: Neuronal-Glial Interactions in Vivo; Ann NY Acad Sci 1999 893: 279-281. [Full Text] [PDF]

DONALD A. FOX, ANN T. POBLENZ, and LIHUA HE: Calcium Overload Triggers Rod Photoreceptor Apoptotic Cell Death in Chemical-Induced and Inherited Retinal Degenerations; Ann NY Acad Sci 1999 893: 282-285. [Full Text] [PDF]

MARINA V. FRANTSEVA, PETER L. CARLEN, and JOSE L. PEREZ VELAZQUEZ: Molecular Mechanisms of Free Radical Production and Protective Efficacies of Antioxidants in in Vitro Ischemia-Reperfusion; Ann NY Acad Sci 1999 893: 286-289. [Full Text] [PDF]

L. FRÖLICH, D. BLUM-DEGEN, P. RIEDERER, and S. HOYER: A Disturbance in the Neuronal Insulin Receptor Signal Transduction in Sporadic Alzheimer's Disease; Ann NY Acad Sci 1999 893: 290-293. [Full Text] [PDF]

LAURA GASPARINI, ROBERTA GHIDONI, ANTONELLA C. ALBERICI, LUISA BENUSSI, DANIELE MORATTO, MARCO TRABUCCHI, JOHN H. GROWDON, ROGER M. NITSCH, and GIULIANO BINETTI: Modulation of Presenilin-1 Processing by Nitric Oxide during Apoptosis Induced by Serum Withdrawal and Glucose Deprivation; Ann NY Acad Sci 1999 893: 294-297. [Full Text] [PDF]

DONALD S. HIGGINS, KARI R. HOYT, CORINNE BAIC, JESSICA VENSEL, and MATTHEW SULKA: Metabolic and Glutamatergic Disturbances in the Huntington's Disease Transgenic Mouse; Ann NY Acad Sci 1999 893: 298-300. [Full Text] [PDF]

SIEGFRIED HOYER and HEINRICH LANNERT: Inhibition of the Neuronal Insulin Receptor Causes Alzheimer-like Disturbances in Oxidative/Energy Brain Metabolism and in Behavior in Adult Rats; Ann NY Acad Sci 1999 893: 301-303. [Full Text] [PDF]

R. KAPOOR, M. DAVIES, and K. J. SMITH: Temporary Axonal Conduction Block and Axonal Loss in Inflammatory Neurological Disease: A Potential Role for Nitric Oxide?; Ann NY Acad Sci 1999 893: 304-308. [Full Text] [PDF]

T. KEKELIDZE, I. KHAIT, A. TOGLIATTI, J. BENZYCRY, R. MULKERN, and D. HOLTZMAN: Maturational Changes in Rabbit Brain Phosphocreatine and Creatine Kinase; Ann NY Acad Sci 1999 893: 309-313. [Full Text] [PDF]

AUTUMN M. KLEIN, NEIL W. KOWALL, and ROBERT J. FERRANTE: Neurotoxicity and Oxidative Damage of Beta Amyloid 1-42 versus Beta Amyloid 1-40 in the Mouse Cerebral Cortex; Ann NY Acad Sci 1999 893: 314-320. [Full Text] [PDF]

BRUCE S. KRISTAL and ABRAHAM M. BROWN: Ganglioside GD3, the Mitochondrial Permeability Transition, and Apoptosis; Ann NY Acad Sci 1999 893: 321-324. [Full Text] [PDF]

D. K. LAHIRI and C. GHOSH: Interactions between Melatonin, Reactive Oxygen Species, and Nitric Oxide; Ann NY Acad Sci 1999 893: 325-330. [Full Text] [PDF]

D. K. LAHIRI, Y. XU, J. KLAUNIG, O. BAIYEWU, A. OGUNNIYI, K. HALL, H. HENDRIE, and A. SAHOTA: Effect of Oxidative Stress on DNA Damage and ß-Amyloid Precursor Proteins in Lymphoblastoid Cell Lines from a Nigerian Population; Ann NY Acad Sci 1999 893: 331-336. [Full Text] [PDF]

STEFAN M. LEE, MONICA D. WONG, AMIR SAMII, and DAVID A. HOVDA: Evidence for Energy Failure following Irreversible Traumatic Brain Injury; Ann NY Acad Sci 1999 893: 337-340. [Full Text] [PDF]

LI-ING LIU, S. I. RAPOPORT, and K. CHANDRASEKARAN: Regulation of Mitochondrial Gene Expression in Differentiated PC12 Cells; Ann NY Acad Sci 1999 893: 341-344. [Full Text] [PDF]

WILLIAM F. MARAGOS, REBEKAH J. JAKEL, M. DATHAN CHESNUT, JAMES W. GEDDES, and LINDA P. DWOSKIN: Does Dopamine Contribute to Striatal Damage Caused by Impaired Mitochondrial Function?; Ann NY Acad Sci 1999 893: 345-349. [Full Text] [PDF]

SATOSHI MINOSHIMA, DONNA J. CROSS, NORMAN L. FOSTER, THOMAS R. HENRY, and DAVID E. KUHL: Discordance between Traditional Pathologic and Energy Metabolic Changes in Very Early Alzheimer's Disease: Pathophysiological Implications; Ann NY Acad Sci 1999 893: 350-352. [Full Text] [PDF]

J. L. MOTT, D. ZHANG, P. L. FARRAR, S. W. CHANG, and H. P. ZASSENHAUS: Low Frequencies of Mitochondrial DNA Mutations Cause Cardiac Disease in the Mouse; Ann NY Acad Sci 1999 893: 353-357. [Full Text] [PDF]

O. MYHRE, T. A. VESTAD, E. SAGSTUEN, H. AARNES, and F. FONNUM: Effects of the Solvent 1,2,4-Trimethylcyclohexane on Respiratory Burst in Human Neutrophil Granulocytes: A Chemiluminescence and Electron Paramagnetic Resonance Spectrometry Study; Ann NY Acad Sci 1999 893: 358-361. [Full Text] [PDF]

AKIHIKO NUNOMURA, GEORGE PERRY, KEISUKE HIRAI, GJUMRAKCH ALIEV, ATSUSHI TAKEDA, SHIGERU CHIBA, and MARK A. SMITH: Neuronal RNA Oxidation in Alzheimer's Disease and Down's Syndrome; Ann NY Acad Sci 1999 893: 362-364. [Full Text] [PDF]

ALEXANDER PANOV, TRACY OBERTONE, JULIE BENNETT-DESMELIK, and J. TIMOTHY GREENAMYRE: Ca²⁺-Dependent Permeability Transition and Complex I Activity in Lymphoblast Mitochondria from Normal Individuals and Patients with Huntington's or Alzheimer's Disease; Ann NY Acad Sci 1999 893: 365-368. [Full Text] [PDF]

J. L. PEREZ VELAZQUEZ, M. V. FRANTSEVA, D. HUZAR, C. GUEZURIAN, and P. L. CARLEN: Mitochondrial Porin, a Novel Target to Prevent Ischemia-Induced Neurodegeneration?; Ann NY Acad Sci 1999 893: 369-371. [Full Text] [PDF]

S. PORAT and R. SIMANTOV: Bcl-2 and p53: Role in Dopamine-Induced Apoptosis and Differentiation; Ann NY Acad Sci 1999 893: 372-375. [Full Text] [PDF]

ANNA BAL-PRICE, VILMA BORUTAITE, and GUY C. BROWN: Mitochondria Mediate Nitric Oxide-Induced Cell Death; Ann NY Acad Sci 1999 893: 376-378. [Full Text] [PDF]

MARIE LUISE RAO, DIETER LÜTJOHANN, MICHAEL LUDWIG, and HEIKE KÖLSCH: Induction of Apoptosis and Necrosis in Human Neuroblastoma Cells by Cholesterol Oxides; Ann NY Acad Sci 1999 893: 379-381. [Full Text] [PDF]

HENRY RODRIGUEZ and STEVEN A. AKMAN: Measurement of Oxidative DNA Damage in the Human p53 and pgk1 Gene at Nucleotide Resolution; Ann NY Acad Sci 1999 893: 382-385. [Full Text] [PDF]

AVITAL SCHURR, RALPHIEL S. PAYNE, MICHAEL T. TSENG, JAMES J. MILLER, and BENJAMIN M. RIGOR: The Glucose Paradox in Cerebral Ischemia: New Insights; Ann NY Acad Sci 1999 893: 386-390. [Full Text] [PDF]

LUCA SCORRANO, VALERIA PETRONILLI, RAFFAELE COLLONA, FABIO DI LISA, and PAOLO BERNARDI: Interactions of Chloromethyltetramethylrosamine (Mitotracker Orange^TM) with Isolated Mitochondria and Intact Cells; Ann NY Acad Sci 1999 893: 391-395. [Full Text] [PDF]

SO YOUNG SEO, EUN YOUNG KIM, HARRIET KIM, ILO JOU, and BYOUNG JOO GWAG: Attenuation of Neuronal Death by NMDA and Oxygen-Glucose Deprivation in Cortical Neurons Maintained in High Glucose; Ann NY Acad Sci 1999 893: 396-399. [Full Text] [PDF]

R. STONE, V. C. STEWART, R. D. HURST, J. B. CLARK, and S. J. R. HEALES: Astrocyte Nitric Oxide Causes Neuronal Mitochondrial Damage, but Antioxidant Release Limits Neuronal Cell Death; Ann NY Acad Sci 1999 893: 400-403. [Full Text] [PDF]

KATHRYN G. TODD and ROGER F. BUTTERWORTH: Mechanisms of Selective Neuronal Cell Death due to Thiamine Deficiency; Ann NY Acad Sci 1999 893: 404-411. [Full Text] [PDF]

LASZLO TRETTER and VERA ADAM-VIZI: Inhibition of ${alpha}$ -Ketoglutarate Dehydrogenase due to H₂O₂-Induced Oxidative Stress in Nerve Terminals; Ann NY Acad Sci 1999 893: 412-416. [Full Text] [PDF]

R. F. VILLA, A. D'ANGELO, and A. GORINI: ATPases of Synaptic Plasma Membranes and Vesicles from Rat Cerebral Cortex during Aging and Hypoxia; Ann NY Acad Sci 1999 893: 417-420. [Full Text] [PDF]

HELLE S. WAAGEPETERSEN, URSULA SONNEWALD, HONG QU, and ARNE SCHOUSBOE: Mitochondrial Compartmentation at the Cellular Level: Astrocytes and Neurons; Ann NY Acad Sci 1999 893: 421-426. [Full Text] [PDF]

FALK ROBERT WIEDEMANN, KIRSTIN WINKLER, HARTMUT LINS, CLAUS-W. WALLESCH, and WOLFRAM S. KUNZ: Detection of Respiratory Chain Defects in Cultivated Skin Fibroblasts and Skeletal Muscle of Patients with Parkinson's Disease; Ann NY Acad Sci 1999 893: 426-429. [Full Text] [PDF]

HIROSHI YASUDA: Prevention of Neurodegeneration by a Neuroprotective Radical Scavenger; Ann NY Acad Sci 1999 893: 430-433. [Full Text] [PDF]

JOHN P. BLASS: Conference Summary: Mitochondria, Neurodegenerative Diseases, and Selective Neuronal Vulnerability; Ann NY Acad Sci 1999 893: 434-439. [Full Text] [PDF]