ANNALS ONLINE -- Table of Contents (December 2002, 973)

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Marc Diederich: Preface; Ann NY Acad Sci 2002 973: xv. [Full Text] [PDF]

Part I. Signal Transduction in Health and Disease:

ANATOLIJ P. POTAPOV and EDGAR WINGENDER: Representing the Architecture of Signal Transduction Networks in an Algebraic Form: Protein Target Finding; Ann NY Acad Sci 2002 973: 1-2. [Full Text] [PDF]

SIMON ALBERTI and JÖRG HÖHFELD: Molecular Chaperones in the Regulation of Signal Transduction; Ann NY Acad Sci 2002 973: 3-4. [Full Text] [PDF]

GIOVANNA BERRUTI and ENZO MARTEGANI: mUBPy and MSJ-1, a Deubiquitinating Enzyme and a Molecular Chaperone Specifically Expressed in Testis, Associate with the Acrosome and Centrosome in Mouse Germ Cells; Ann NY Acad Sci 2002 973: 5-7. [Full Text] [PDF]

E. M. SCHNEIDER, A. M. NIESS, I. LORENZ, H. NORTHOFF, and E. FEHRENBACH: Inducible Hsp70 Expression Analysis after Heat and Physical Exercise: Transcriptional, Protein Expression, and Subcellular Localization; Ann NY Acad Sci 2002 973: 8-12. [Full Text] [PDF]

QIAN YANG, YI XIE, and JOSEPH W. DePIERRE: Suppression of Adaptive Immune Responses: A Novel Mechanism by Which Peroxisome Proliferators Exert Antiinflammatory Effects?; Ann NY Acad Sci 2002 973: 13-16. [Full Text] [PDF]

YI XIE, QIAN YANG, and JOSEPH W. DePIERRE: The Effects of Peroxisome Proliferators on Global Lipid Homeostasis and the Possible Significance of These Effects to Other Responses to These Xenobiotics: An Hypothesis; Ann NY Acad Sci 2002 973: 17-25. [Abstract] [Full Text] [PDF]

THIERRY FOURNIER, LAETITIA PAVAN, ANNE TARRADE, KRISTINA SCHOONJANS, JOHAN AUWERX, CECILE ROCHETTE-EGLY, and DANIELE EVAIN-BRION: The Role of PPAR- ${gamma}$ /RXR- ${alpha}$ Heterodimers in the Regulation of Human Trophoblast Invasion; Ann NY Acad Sci 2002 973: 26-30. [Abstract] [Full Text] [PDF]

PETER BRENNEISEN, HELMUT SIES, and KARIN SCHARFFETTER-KOCHANEK: Ultraviolet-B Irradiation and Matrix Metalloproteinases: From Induction via Signaling to Initial Events; Ann NY Acad Sci 2002 973: 31-43. [Abstract] [Full Text] [PDF]

FLORENCE CHAINIAUX, JOSÉ REMACLE, and OLIVIER TOUSSAINT: Exposure of Human Skin Diploid Fibroblasts to Repeated Subcytotoxic Doses of Ultraviolet-B Induces the Overexpression of Transforming Growth Factor-ß1 mRNA; Ann NY Acad Sci 2002 973: 44-48. [Abstract] [Full Text] [PDF]

ROSA MARTÍNEZ, ROSAURA NAVARRO, CÉSAR MARTÍN, IGOR AURREKOETXEA, M. LUISA HERNÁNDEZ, MERCEDES LACORT, JOSÉ IGNACIO RUIZ-SANZ, and M. BEGOÑA RUIZ-LARREA: Doxorubicin Increases Intracellular Diacylglycerol by the Mobilization of Choline-Enriched Phospholipids in Rat Hepatocytes; Ann NY Acad Sci 2002 973: 49-51. [Full Text] [PDF]

ROSA MARTÍNEZ, ROSAURA NAVARRO, CÉSAR MARTÍN, IGOR AURREKOETXEA, M. LUISA HERNÁNDEZ, MERCEDES LACORT, JOSÉ IGNACIO RUIZ-SANZ, and M. BEGOÑA RUIZ-LARREA: Intracellular Diacylglycerol Accumulation Induced by Doxorubicin in Rat Hepatocytes: Potential Involvement of Phospholipases C and D; Ann NY Acad Sci 2002 973: 52-56. [Full Text] [PDF]

MARGARETE GOPPELT-STRUEBE, JULIANE HEUSINGER-RIBEIRO, and BARBARA FISCHER: Dual Role of Cytochalasin D in the Regulation of Connective Tissue Growth Factor; Ann NY Acad Sci 2002 973: 57-59. [Full Text] [PDF]

SIMONE BARBERO, ADRIANA BAJETTO, RUDY BONAVIA, CAROLA PORCILE, PATRIZIA PICCIOLI, PAOLO PIRANI, JEAN LOUIS RAVETTI, GIANLUIGI ZONA, RENATO SPAZIANTE, TULLIO FLORIO, and GENNARO SCHETTINI: Expression of the Chemokine Receptor CXCR4 and Its Ligand Stromal Cell-Derived Factor 1 in Human Brain Tumors and Their Involvement in Glial Proliferation in Vitro; Ann NY Acad Sci 2002 973: 60-69. [Abstract] [Full Text] [PDF]

F. NEFF, C. NOELKER, K. EGGERT, and J. SCHLEGEL: Signaling Pathways Mediate the Neuroprotective Effects of GDNF; Ann NY Acad Sci 2002 973: 70-74. [Abstract] [Full Text] [PDF]

YASUHIRO KUMEI, HIROSHI NAKAMURA, SADAO MORITA, HIDEO AKIYAMA, MASAHIKO HIRANO, KEI'ICHI OHYA, KEN'ICHI SHINOMIYA, and HITOYATA SHIMOKAWA: Space Flight and Insulin-like Growth Factor-I Signaling in Rat Osteoblasts; Ann NY Acad Sci 2002 973: 75-78. [Abstract] [Full Text] [PDF]

CRISTINA ALBANESI, MONICA FEDERICI, MARIA L. GIUSTIZIERI, CLAUDIA SCARPONI, and GIAMPIERO GIROLOMONI: Suppressor of Cytokine Signaling-1 Inhibits Interferon-g-Induced Activation of Human Keratinocytes; Ann NY Acad Sci 2002 973: 79-82. [Full Text] [PDF]

Y. BENMESSAHEL, R. GUENNOUN, F. CADEPOND, E. E. BAULIEU, M. SCHUMACHER, and G. GROYER: Expression of Steroidogenic Acute Regulatory Protein in Cultured Schwann Cells and Its Regulation by cAMP; Ann NY Acad Sci 2002 973: 83-87. [Abstract] [Full Text] [PDF]

T. PRIEGO, I. IBAÑEZ DE CÁCERES, A. I. MARTÍN, M. A. VILLANÚA, and A. LÓPEZ-CALDERÓN: Hepatic Insulin-like Growth Factor-I Binding Protein 3 Gene Expression in Rats with Endotoxic Shock: The Role of Glucocorticoids; Ann NY Acad Sci 2002 973: 88-90. [Abstract] [Full Text] [PDF]

H.-G. BERNSTEIN, A. HEINEMANN, D. KRELL, C. MAWRIN, H. BIELAU, P. DANOS, S. DIEKMANN, G. KEILHOFF, B. BOGERTS, and B. BAUMANN: Further Immunohistochemical Evidence for Impaired NO Signaling in the Hypothalamus of Depressed Patients; Ann NY Acad Sci 2002 973: 91-93. [Abstract] [Full Text] [PDF]

SARA ARENA, ALESSANDRA PATTAROZZI, STEFANO THELLUNG, VALENTINA VILLA, ALESSANDRO CORSARO, ALESSANDRO MASSA, FABRIZIO DIANA, GIUSEPPE SPOTO, SABRINA FORCELLA, GIANLUCA DAMONTE, MIRELLA FILOCAMO, UMBERTO BENATTI, GENNARO SCHETTINI, and TULLIO FLORIOA: Nitric Oxide Production Stimulated by the Basic Fibroblast Growth Factor Requires the Synthesis of Ceramide; Ann NY Acad Sci 2002 973: 94-104. [Abstract] [Full Text] [PDF]

DAVID TULASNE, REJANE PAUMELLE, CATHERINE LEROY, SYLVIE REVENEAU, BERNARD VANDENBUNDER, and VERONIQUE FAFEUR: Involvement of RAS-ERK Signaling in Multiple Biological Responses to HGF/SF; Ann NY Acad Sci 2002 973: 105-108. [Full Text] [PDF]

LARA TICKENBROCK, JANINA CRAMER, INGRID VETTER, and OLIVER MÜLLER: Structure of the Amino-Terminal Nuclear Export Domain of the APC Tumor Suppressor Protein; Ann NY Acad Sci 2002 973: 109-111. [Full Text] [PDF]

S. WEG-REMERS, H. PONTA, P. HERRLICH, and H. KÖNIG: Antagonistic Signaling Pathways Regulate Alternative Splicing of CD44 in T Cells; Ann NY Acad Sci 2002 973: 112-115. [Full Text] [PDF]

LUC DUPUIS, FRÉDÉRIQUE RENE, FRANCK DI SCALA, JOSE-LUIS GONZALEZ DE AGUILAR, MARC DE TAPIA, and JEAN-PHILIPPE LOEFFLER: Denervation Is Not a Primary Cause of Prion Protein Down-Regulation Occurring in the Spinal Cord of a Transgenic Model of Amyotrophic Lateral Sclerosis; Ann NY Acad Sci 2002 973: 116-119. [Full Text] [PDF]

TARIK ISSAD, NICOLAS BOUTE, and KARINE PERNET: The Activity of the Insulin Receptor Assessed by Bioluminescence Resonance Energy Transfer; Ann NY Acad Sci 2002 973: 120-123. [Abstract] [Full Text] [PDF]

ELINE MENU, FILIP BRAET, MAARTEN TIMMERS, IVAN VAN RIET, BEN VAN CAMP, and KARIN VANDERKERKEN: The F-Actin Content of Multiple Myeloma Cells as a Measure of Their Migration; Ann NY Acad Sci 2002 973: 124-136. [Abstract] [Full Text] [PDF]

ENZO MARTEGANI, MICHELA CERIANI, RENATA TISI, and GIOVANNA BERRUTI: Cloning and Characterization of a New Ral-GEF Expressed in Mouse Testis; Ann NY Acad Sci 2002 973: 135-137. [Full Text] [PDF]

REEMA GOEL and JOSEPH J. BALDASSARE: ß-Arrestin 1 Couples Thrombin to the Rapid Activation of the Akt Pathway; Ann NY Acad Sci 2002 973: 138-141. [Abstract] [Full Text] [PDF]

POLLY J. PHILLIPS-MASON, REEMA GOEL, and JOSEPH J. BALDASSARE: ${alpha}$ -Thrombin Activates Akt via a Nonreceptor Tyrosine Kinase in IIC9 Cells; Ann NY Acad Sci 2002 973: 142-144. [Abstract] [Full Text] [PDF]

WILFRID RUL, OLIVIER ZUGASTI, PIERRE ROUX, CAROLE PEYSSONNAUX, ALAIN EYCHENE, THOMAS F. FRANKE, PHILIPPE LENORMAND, PHILIPPE FORT, and URSZULA HIBNER: Activation of ERK, Controlled by Rac1 and Cdc42 via Akt, Is Required for Anoikis; Ann NY Acad Sci 2002 973: 145-148. [Abstract] [Full Text] [PDF]

E. SCHÖNHERR, B. LEVKAU, L. SCHAEFER, H. KRESSE, and K. WALSH: Decorin Affects Endothelial Cells by Akt-Dependent and -Independent Pathways; Ann NY Acad Sci 2002 973: 149-152. [Abstract] [Full Text] [PDF]

Part II. Apoptosis Pathways as Targets for Therapeutic Applications:

HYE-KYUNG NA and YOUNG-JOON SURH: Induction of Cyclooxygenase-2 in Ras-Transformed Human Mammary Epithelial Cells Undergoing Apoptosis; Ann NY Acad Sci 2002 973: 153-160. [Abstract] [Full Text] [PDF]

DARREN O'BRIEN, TERRY O'CONNOR, FERGUS SHANAHAN, and JOE O'CONNELL: Activation of the p38 MAPK and ERK1/2 Pathways Is Required for Fas-Induced IL-8 Production in Colonic Epithelial Cells; Ann NY Acad Sci 2002 973: 161-165. [Abstract] [Full Text] [PDF]

JAN M. H. VAN DEN BRANDE, MAIKEL P. PEPPELENBOSCH, and SANDER J. H. VAN DEVENTER: Treating Crohn's Disease by Inducing T Lymphocyte Apoptosis; Ann NY Acad Sci 2002 973: 166-180. [Abstract] [Full Text] [PDF]

G. SÁRMAY, G. KONCZ, Cs. BODOR, D. KÖVESDI, R. GÁTI, and J. GERGELY: Signaling Pathways Leading to Apoptosis or Survival in Immature and Mature B Cells; Ann NY Acad Sci 2002 973: 181-185. [Abstract] [Full Text] [PDF]

MARIE-PIERRE COURAGEOT, SANDRINE LEPINE, FRANCOISE GIRAUD, and JEAN-CLAUDE SULPICE: Extracellular ATP Induces Phosphatidylserine Externalization Earlier than Nuclear Apoptotic Events in Thymocytes; Ann NY Acad Sci 2002 973: 186-189. [Abstract] [Full Text] [PDF]

SANDRINE LÉPINE, BORIS LAKATOS, PIERRE MAZIERE, MARIE-PIERRE COURAGEOT, JEAN-CLAUDE SULPICE, and FRANCOISE GIRAUD: Involvement of Sphingosine in Dexamethasone-Induced Thymocyte Apoptosis; Ann NY Acad Sci 2002 973: 190-193. [Abstract] [Full Text] [PDF]

VIKTOR MENART, IRENA FONDA, MAJA KENIG, and VLADKA GABERC POREKAR: Increased in Vitro Cytotoxicity of TNF- ${alpha}$ Analog LK-805 Is Based on the Interaction with Cell Surface Heparan Sulfate Proteoglycan; Ann NY Acad Sci 2002 973: 194-206. [Abstract] [Full Text] [PDF]

MURIEL DAVID, JACQUES BERTOGLIO, and JOSIANE PIERRE: TNF- ${alpha}$ Potentiates IL-4/IL-13-Induced IL-13R ${alpha}$ 2 Expression; Ann NY Acad Sci 2002 973: 207-209. [Full Text] [PDF]

SAVERIA PASTORE, FRANCESCA MASCIA, VALENTINA MARIANI, and GIAMPIERO GIROLOMONI: Epidermal Growth Factor Receptor Ligands and Tumor Necrosis Factor- ${alpha}$ Coregulate Chemokine Expression in Human Keratinocytes; Ann NY Acad Sci 2002 973: 210-213. [Full Text] [PDF]

OLIVIER DISSON, MICHAEL HAHNE, URSZULA HIBNER, and HERVÉ LERAT: Hepatocytes Transgenic for the Full Hepatitis C Virus Open Reading Frame Are Resistant to Fas-Induced Cell Death; Ann NY Acad Sci 2002 973: 214-217. [Full Text] [PDF]

M. REFSNES, H. KERSTEN, P. E. SCHWARZE, and M. LÅG: Involvement of Protein Kinase C in Fluoride-Induced Apoptosis in Different Types of Lung Cells; Ann NY Acad Sci 2002 973: 218-220. [Full Text] [PDF]

SANG-OH YOON, SOO-JIN PARK, and AN-SIK CHUNG: Selenite Inhibits Apoptosis via Activation of the PI3-K/Akt Pathway; Ann NY Acad Sci 2002 973: 221-223. [Full Text] [PDF]

J. SCHLEGEL, G. DURCHSCHLAG, G. PIONTEK, and A. L. GROSU: Activation of the Phosphatidylinositol-3'-Kinase/Protein Kinase B-Dependent Antiapoptotic Pathway Plays an Important Role in the Development of Radioresistance of Human Glioma Cells; Ann NY Acad Sci 2002 973: 224-227. [Full Text] [PDF]

JUNG-HEE JANG and YOUNG-JOON SURH: ß-Amyloid Induces Oxidative DNA Damage and Cell Death through Activation of c-Jun N Terminal Kinase; Ann NY Acad Sci 2002 973: 228-236. [Abstract] [Full Text] [PDF]

METTE GEORGI WILLESEN, STEEN GAMMELTOFT, and ELISABETTA VAUDANO: Activation of the c-Jun N Terminal Kinase Pathway in an Animal Model of Parkinson's Disease; Ann NY Acad Sci 2002 973: 237-240. [Abstract] [Full Text] [PDF]

TAE IL KIM, SOO HYUN JIN, EUN HYE KANG, SUNG KWAN SHIN, KANG YELL CHOI, and WON HO KIM: The Role of Mitogen-Activated Protein Kinases and Their Relationship with NF- ${kappa}$ B and PPAR ${gamma}$ in Indomethacin-Induced Apoptosis of Colon Cancer Cells; Ann NY Acad Sci 2002 973: 241-245. [Abstract] [Full Text] [PDF]

BEATRIZ MONTANER and RICARDO PÉREZ-TOMÁS: Prodigiosin Induces Caspase-9 and Caspase-8 Activation and Cytochrome C Release in Jurkat T Cells; Ann NY Acad Sci 2002 973: 246-249. [Abstract] [Full Text] [PDF]

KATARZYNA PIWOCKA, ANNA BIELAK-MIJEWSKA, and EWA SIKORA: Curcumin Induces Caspase-3-Independent Apoptosis in Human Multidrug-Resistant Cells; Ann NY Acad Sci 2002 973: 250-254. [Abstract] [Full Text] [PDF]

JINSIL SEONG, SUNG HEE KIM, HONG RYUL PYO, EUN JI CHUNG, and CHANG OK SUH: Low-Dose Radiation-Induced Adaptive Response in the Murine System; Ann NY Acad Sci 2002 973: 255-257. [Full Text] [PDF]

M. HORKY, V. KOTALA, M. ANTON, and J. WESIERSKA-GADEK: Nucleolus and Apoptosis; Ann NY Acad Sci 2002 973: 258-264. [Abstract] [Full Text] [PDF]

Part III. Cell Cycle Control:

NATHAN H. LENTS, SUSAN M. KEENAN, CLIFFORD BELLONE, and JOSEPH J. BALDASSARE: Activation and Phosphorylation on Thr-160 of Nuclear-Targeted CDK2 Is ERK Dependent; Ann NY Acad Sci 2002 973: 265-267. [Full Text] [PDF]

ELVIRA CRESCENZI, MARIA SANNINO, GILDA TONZIELLO, and GIUSEPPE PALUMBO: Association of Bcl-2 with Cyclin A/Cdk-2 Complex and Its Effects on Cdk-2 Activity; Ann NY Acad Sci 2002 973: 268-271. [Abstract] [Full Text] [PDF]

VÉRONIQUE MARTEL, ODILE FILHOL, ARSENIO NUEDA, and CLAUDE COCHET: Dynamic Localization/Association of Protein Kinase CK2 Subunits in Living Cells: A Role in Its Cellular Regulation?; Ann NY Acad Sci 2002 973: 272-277. [Abstract] [Full Text] [PDF]

JOHN A. MARWICK, PAUL KIRKHAM, PETER S. GILMOUR, KENNETH DONALDSON, WILLIAM MacNEE, and IRFAN RAHMAN: Cigarette Smoke-Induced Oxidative Stress and TGF-ß₁ Increase p21^waf1/cip1 Expression in Alveolar Epithelial Cells; Ann NY Acad Sci 2002 973: 278-283. [Abstract] [Full Text] [PDF]

RUTA NAVAKAUSKIENE, GRAZINA TREIGYTE, ARUNAS GINEITIS, and KARL-ERIC MAGNUSSON: Assessment of p16, p21, and p27 in Granulocytic Differentiation of Human Promyelocytic HL-60 Cell Line; Ann NY Acad Sci 2002 973: 284-286. [Full Text] [PDF]

Part IV. Signal Transduction, Stress Response, and Aging:

LEOPOLD FLOHÉ, CARLO FORESTA, ANDREA GAROLLA, MATILDE MAIORINO, ANTONELLA ROVERI, and FULVIO URSINI: Metamorphosis of the Selenoprotein PHGPx during Spermatogenesis; Ann NY Acad Sci 2002 973: 287-288. [Full Text] [PDF]

A. KYRIAKOPOULOS, H. BERTELSMANN, A. GRAEBERT, B. HOPPE, M. KÜHBACHER, and D. BEHNE: Detection and Characterization of Membrane-Bound Selenoproteins in the Kidney of the Rat; Ann NY Acad Sci 2002 973: 289-292. [Abstract] [Full Text] [PDF]

PATRIZIA FATTORETTI, CARLO BERTONI-FREDDARI, TIZIANA CASOLI, GIUSEPPINA DI STEFANO, MORENO SOLAZZI, and BELINDA GIORGETTI: Decreased Expression of Glucose Transport Protein (Glut3) in Aging and Vitamin E Deficiency; Ann NY Acad Sci 2002 973: 293-296. [Full Text] [PDF]

JEAN-LOUIS FRENDO, PATRICE THÉROND, JEAN GUIBOURDENCHE, MICHEL VIDAUD, and DANIèLE EVAIN-BRIONA: Implication of Copper Zinc Superoxide Dismutase (SOD-1) in Human Placenta Development; Ann NY Acad Sci 2002 973: 297-301. [Full Text] [PDF]

TAMAS FULOP, JR., NADINE DOUZIECH, ANIS LARBI, and GILLES DUPUIS: The Role of Lipid Rafts in T Lymphocyte Signal Transduction with Aging; Ann NY Acad Sci 2002 973: 302-304. [Full Text] [PDF]

TAMAS FULOP, JR., ANIS LARBI, ANNIE LINTEAU, SÉBASTIEN DESGEORGES, and NADINE DOUZIECH: The Role of Mcl-1 and Bax Expression Alteration in the Decreased Rescue of Human Neutrophils from Apoptosis by GM-CSF with Aging; Ann NY Acad Sci 2002 973: 305-308. [Full Text] [PDF]

ALEXEI TERMAN and SARA SANDBERG: Proteasome Inhibition Enhances Lipofuscin Formation; Ann NY Acad Sci 2002 973: 309-312. [Abstract] [Full Text] [PDF]

T. CASOLI, G. DI STEFANO, P. FATTORETTI, A. DELFINO, M. SOLAZZI, and C. BERTONI-FREDDARI: Effects of Ethanol on GAP-43 Levels in Hippocampus and Cerebellum of Aged Rats; Ann NY Acad Sci 2002 973: 313-316. [Full Text] [PDF]

GIRISH J. KOTWAL, DEBOMOY K. LAHIRI, and RAMONA HICKS: Potential Intervention by Vaccinia Virus Complement Control Protein of the Signals Contributing to the Progression of Central Nervous System Injury to Alzheimer's Disease; Ann NY Acad Sci 2002 973: 317-322. [Abstract] [Full Text] [PDF]

CLAUDIO RUSSO, VIRGINIA DOLCINI, SERENA SALIS, VALENTINA VENEZIA, ELISABETTA VIOLANI, PIA CARLO, NICOLA ZAMBRANO, TOMMASO RUSSO, and GENNARO SCHETTINI: Signal Transduction through Tyrosine-Phosphorylated Carboxy-Terminal Fragments of APP via an Enhanced Interaction with Shc/Grb2 Adaptor Proteins in Reactive Astrocytes of Alzheimer's Disease Brain; Ann NY Acad Sci 2002 973: 323-333. [Abstract] [Full Text] [PDF]

D. K. LAHIRI, G. J. KOTWAL, M. R. FARLOW, A. SIMA, W. KUPSKY, F. H. SARKAR, and K. SAMBAMURTI: The Role of the Carboxyl-Terminal Fragments of Amyloid Precursor Protein in Alzheimer's Disease; Ann NY Acad Sci 2002 973: 334-339. [Abstract] [Full Text] [PDF]

D. K. LAHIRI, G. M. ALLEY, Y.-W. GE, and Y. DU: Functional Characterization of the 5'-Regulatory Region of the Murine Apolipoprotein Gene; Ann NY Acad Sci 2002 973: 340-344. [Abstract] [Full Text] [PDF]

Part V. Kinases as Targets for Novel Therapeutic Applications:

MARTINE TORRES and HENRY JAY FORMAN: Vanadate Inhibition of Protein Tyrosine Phosphatases Mimics Hydrogen Peroxide in the Activation of the ERK Pathway in Alveolar Macrophages; Ann NY Acad Sci 2002 973: 345-348. [Full Text] [PDF]

BERNT VAN DEN BLINK, TESSA TEN HOVE, GIJS R. VAN DEN BRINK, MAIKEL P. PEPPELENBOSCH, and SANDER J.H. VAN DEVENTER: From Extracellular to Intracellular Targets, Inhibiting MAP Kinases in Treatment of Crohn's Disease; Ann NY Acad Sci 2002 973: 349-358. [Abstract] [Full Text] [PDF]

SITHIPORN AGTHONG and DAVID R. TOMLINSON: Inhibition of p38 MAP Kinase Corrects Biochemical and Neurological Deficits in Experimental Diabetic Neuropathy; Ann NY Acad Sci 2002 973: 359-362. [Abstract] [Full Text] [PDF]

HARRY ENGEMANN, D. KÖGEL, S. MANDERSCHEID, U. PREUSS, and K. H. SCHEIDTMANN: Elucidation of Transcriptional Elements and the Genomic Structure of DAP-like Kinase; Ann NY Acad Sci 2002 973: 363-367. [Full Text] [PDF]

MIRELLA NARDINI, CRISTINA SCACCINI, and FABIO VIRGILI: Modulation of Kinase Activity by Polyphenols; Ann NY Acad Sci 2002 973: 368-370. [Full Text] [PDF]

JINSIL SEONG, SUNG HEE KIM, and CHANG OK SUH: Enhancement of Radioresponse of Murine Tumors by ERK Inhibitor; Ann NY Acad Sci 2002 973: 371-373. [Full Text] [PDF]

Part VI. Transcriptional Regulation Paradigms:

MOSHE OREN, ALEXANDER DAMALAS, TANYA GOTTLIEB, DAN MICHAEL, JAN TAPLICK, JUAN FERNANDO MARTINEZ LEAL, RUTH MAYA, MIRI MOAS, RONY SEGER, YOICHI TAYA, and AVRI BEN-ZE'EV: Regulation of p53: Intricate Loops and Delicate Balances; Ann NY Acad Sci 2002 973: 374-383. [Abstract] [Full Text] [PDF] Acknowledgment

YU-CHING CHANG, HSUEH-WEI CHANG, CHU-BIN LIAO, and YIN-CHANG LIU: The Roles of p53, DNA Repair, and Oxidative Stress in Ultraviolet C Induction of Proliferating Cell Nuclear Antigen Expression; Ann NY Acad Sci 2002 973: 384-391. [Abstract] [Full Text] [PDF]

ALOK C. BHARTI and BHARAT B. AGGARWAL: Chemopreventive Agents Induce Suppression of Nuclear Factor- ${kappa}$ B Leading to Chemosensitization; Ann NY Acad Sci 2002 973: 392-395. [Abstract] [Full Text] [PDF]

YOUNG-JOON SURH, JI-YOON LEE, KANG-JU CHOI, and SUNG-RYONG KO: Effects of Selected Ginsenosides on Phorbol Ester-Induced Expression of Cyclooxygenase-2 and Activation of NF- ${kappa}$ B and ERK1/2 in Mouse Skin; Ann NY Acad Sci 2002 973: 396-401. [Abstract] [Full Text] [PDF]

CAROLA PORCILE, PATRIZIA PICCIOLI, SABRINA STANZIONE, ADRIANA BAJETTO, RUDY BONAVIA, SIMONE BARBERO, TULLIO FLORIO, and GENNARO SCHETTINIA: Proteasome Inhibitors Induce Cerebellar Granule Cell Death: Inhibition of Nuclear Factor-kB Activation; Ann NY Acad Sci 2002 973: 402-413. [Abstract] [Full Text] [PDF]

SOO HYUN JIN, TAE IL KIM, DONG SOO HAN, SUNG KWAN SHIN, and WON HO KIM: Thalidomide Suppresses the Interleukin 1ß-Induced NF ${kappa}$ B Signaling Pathway in Colon Cancer Cells; Ann NY Acad Sci 2002 973: 414-418. [Abstract] [Full Text] [PDF]

HIDEAKI KAMATA, TOMOYUKI MANABE, JUNGO KAKUTA, SHIN-ICHI OKA, and HAJIME HIRATA: Multiple Redox Regulation of the Cellular Signaling System Linked to AP-1 and NF ${kappa}$ B: Effects of N-Acetylcysteine and H₂O₂ on the Receptor Tyrosine Kinases, the MAP Kinase Cascade, and I ${kappa}$ B Kinases; Ann NY Acad Sci 2002 973: 419-422. [Full Text] [PDF]

D. LACASA, E. GARCIA DOS SANTOS, M. N. DIEUDONNE, and Y. GIUDICELLI: Rapid Estradiol Activation of AP-1 and CREB in Rat White Adipocytes; Ann NY Acad Sci 2002 973: 423-425. [Full Text] [PDF]

CLAIRE ACQUAVIVA, GUILLAUME BOSSIS, PATRIZIA FERRARA, FRÉDÉRIQUE BROCKLY, ISABELLE JARIEL-ENCONTRE, and MARC PIECHACZYK: Multiple Degradation Pathways for Fos Family Proteins; Ann NY Acad Sci 2002 973: 426-434. [Abstract] [Full Text] [PDF]

E. TEDESCHI, H. SUZUKI, and M. MENEGAZZI: Antiinflammatory Action of EGCG, the Main Component of Green Tea, through STAT-1 Inhibition; Ann NY Acad Sci 2002 973: 435-437. [Full Text] [PDF]

ANNE-LAURENCE BOUTILLIER, EMMANUELLE TRINH, and JEAN-PHILIPPE LOEFFLER: Constitutive Repression of E2F1 Transcriptional Activity through HDAC Proteins Is Essential for Neuronal Survival; Ann NY Acad Sci 2002 973: 438-442. [Full Text] [PDF]

JEAN-PASCAL PIRET, DENIS MOTTET, MARTINE RAES, and CARINE MICHIELS: CoCl₂, a Chemical Inducer of Hypoxia-Inducible Factor-1, and Hypoxia Reduce Apoptotic Cell Death in Hepatoma Cell Line HepG2; Ann NY Acad Sci 2002 973: 443-447. [Abstract] [Full Text] [PDF]

DENIS MOTTET, GAETAN MICHEL, PATRICIA RENARD, NOELLE NINANE, MARTINE RAES, and CARINE MICHIELS: ERK and Calcium in Activation of HIF-1; Ann NY Acad Sci 2002 973: 448-453. [Abstract] [Full Text] [PDF]

A. BAUDHUIN, I. MANFROID, C. VAN DE WEERDT, J. A. MARTIAL, and M. MULLER: Transcription of the Human Prolactin Gene in Mammary Cells; Ann NY Acad Sci 2002 973: 454-458. [Abstract] [Full Text] [PDF]

HESSO FARHAN and HEIDE S. CROSS: Transcriptional Inhibition of CYP24 by Genistein; Ann NY Acad Sci 2002 973: 459-462. [Abstract] [Full Text] [PDF]

Y.-W. GE and D. K. LAHIRI: Regulation of Promoter Activity of the APP Gene by Cytokines and Growth Factors: Implications in Alzheimer's Disease; Ann NY Acad Sci 2002 973: 463-467. [Abstract] [Full Text] [PDF]

STEPHANE LABIALLE, LANDRY GAYET, ERIC MARTHINET, DOMINIQUE RIGAL, and LORIS G. BAGGETTO: Transcriptional Regulation of the Human MDR1 Gene at the Level of the Inverted MED-1 Promoter Region; Ann NY Acad Sci 2002 973: 468-471. [Abstract] [Full Text] [PDF]

TERTIA D. PURVES and DAVID R. TOMLINSON: Diminished Transcription Factor Survival Signals in Dorsal Root Ganglia in Rats with Streptozotocin-Induced Diabetes; Ann NY Acad Sci 2002 973: 472-476. [Abstract] [Full Text] [PDF]

JI HYE SEO, HYEYOUNG KIM, and KYUNG HWAN KIM: Cyclooxygenase-2 Expression by Transcription Factors in Helicobacter pylori-Infected Gastric Epithelial Cells: Comparison between HP 99 and NCTC 11637; Ann NY Acad Sci 2002 973: 477-480. [Abstract] [Full Text] [PDF]

LOUKIA G. TSAPROUNI, KAZUHIRO ITO, NEVILLE PUNCHARD, and IAN M. ADCOCK: Triamcinolone Acetonide and Dexamethasome Suppress TNF- ${alpha}$ -Induced Histone H4 Acetylation on Lysine Residues 8 and 12 in Mononuclear Cells; Ann NY Acad Sci 2002 973: 481-483. [Full Text] [PDF]

FRANÇOISE CADEPOND, CHARBEL MASSAAD, AMALIA TROUSSON, JULIEN GRENIER, GHISLAINE GROYER, ETIENNE BAULIEU, and MICHAEL SCHUMACHER: Steroid Receptors in Various Glial Cell Lines Expression and Functional Studies; Ann NY Acad Sci 2002 973: 484-487. [Abstract] [Full Text] [PDF]

Part VII. Thiols, Protein Thiolation, and Cell Signaling:

DALE A. DICKINSON and HENRY JAY FORMAN: Glutathione in Defense and Signaling: Lessons from a Small Thiol; Ann NY Acad Sci 2002 973: 488-504. [Abstract] [Full Text] [PDF]

AGNES GÖRLACH, THOMAS KIETZMANN, and JOHN HESS: Redox Signaling through NADPH Oxidases: Involvement in Vascular Proliferation and Coagulation; Ann NY Acad Sci 2002 973: 505-507. [Abstract] [Full Text] [PDF]

JEAN-PIERRE JACQUOT, NICOLAS ROUHIER, and ERIC GELHAYE: Redox Control by Dithiol-Disulfide Exchange in Plants: I. The Chloroplastic Systems; Ann NY Acad Sci 2002 973: 508-519. [Abstract] [Full Text] [PDF]

NICOLAS ROUHIER, ERIC GELHAYE, and JEAN-PIERRE JACQUOT: Redox Control by Dithiol-Disulfide Exchange in Plants: II. The Cytosolic and Mitochondrial Systems; Ann NY Acad Sci 2002 973: 520-528. [Abstract] [Full Text] [PDF]

PHILIP EATON and MICHAEL J. SHATTOCK: Purification of Proteins Susceptible to Oxidation at Cysteine Residues: Identification of Malate Dehydrogenase as a Target for S-Glutathiolation; Ann NY Acad Sci 2002 973: 529-532. [Abstract] [Full Text] [PDF]

DOLORES PÉREZ-SALA, EVA CERNUDA-MOROLLÓN, ESTELA PINEDA-MOLINA, and F. JAVIER CAÑADA: Contribution of Covalent Protein Modification to the Antiinflammatory Effects of Cyclopentenone Prostaglandins; Ann NY Acad Sci 2002 973: 533-536. [Abstract] [Full Text] [PDF]

E. KARELSON, R. MAHLAPUU, M. ZILMER, U. SOOMETS, N. BOGDANOVIC, and Ü. LANGEL: Possible Signaling by Glutathione and Its Novel Analogue through Potent Stimulation of Frontocortical G Proteins in Normal Aging and in Alzheimer's Disease; Ann NY Acad Sci 2002 973: 537-540. [Abstract] [Full Text] [PDF]

JEONG YEON SEO, HYEYOUNG KIM, and KYUNG HWAN KIM: Transcriptional Regulation by Thiol Compounds in Helicobacter pylori-Induced Interleukin-8 Production in Human Gastric Epithelial Cells; Ann NY Acad Sci 2002 973: 541-545. [Abstract] [Full Text] [PDF]

MARIA GRAZIA SIGNORELLO, RAFFAELE PASCALE, and GIULIANA LEONCINI: Reactive Oxygen Species Accumulation Induced by Homocysteine in Human Platelets; Ann NY Acad Sci 2002 973: 546-549. [Full Text] [PDF]

A. TACHENY, S. DOS SANTOS, A.-C. HUET, M. VAN STEENBRUGGE, C. MICHIELS, P. HOLVOET, and M. RAES: Effects of Homocysteine on the Cellular Responses of Murine Endothelial Cells Cultured in Vitro; Ann NY Acad Sci 2002 973: 550-554. [Abstract] [Full Text] [PDF]

RAYMOND G. KELLY, KENNETH NALLY, FERGUS SHANAHAN, and JOE O'CONNELL: Type I Insulin-like Growth Factor Receptor Expression on Colorectal Adenocarcinoma Cell Lines Is Decreased in Response to the Chemopreventive Agent N-Acetyl-l-Cysteine; Ann NY Acad Sci 2002 973: 555-558. [Abstract] [Full Text] [PDF]

Part VIII. Signaling by Cell Adhesion Molecules:

A. CHERUBINI, S. PILLOZZI, G. HOFMANN, O. CROCIANI, L. GUASTI, E. LASTRAIOLI, S. POLVANI, A. MASI, A. BECCHETTI, E. WANKE, M. OLIVOTTO, and A. ARCANGELI: HERG K⁺ Channels and ß1 Integrins Interact through the Assembly of a Macromolecular Complex; Ann NY Acad Sci 2002 973: 559-561. [Full Text] [PDF]

JULIE LAFERRIÈRE, FRANÇOIS HOULE, and JACQUES HUOT: Regulation of the Metastatic Process by E-Selectin and Stress-Activated Protein Kinase-2/p38; Ann NY Acad Sci 2002 973: 562-572. [Abstract] [Full Text] [PDF]

HANS W. M. NIESSEN, PAUL A. J. KRIJNEN, CEES A. VISSER, CHRIS J. L. M. MEIJER, and C. ERIK HACK: Intercellular Adhesion Molecule-1 in the Heart; Ann NY Acad Sci 2002 973: 573-585. [Abstract] [Full Text] [PDF]

S. A. ÁSGEIRSDÓTTIR, N. WERNER, G. HARMS, A. VAN DEN BERG, and G. MOLEMA: Analysis of in Vivo Endothelial Cell Activation Applying RT-PCR following Endothelial Cell Isolation by Laser Dissection Microscopy; Ann NY Acad Sci 2002 973: 586-589. [Abstract] [Full Text] [PDF]

CORINNE BARAT and MICHEL J. TREMBLAY: Adhesion Molecules as Costimulators: ICAM-3 Signaling Potentiates CD3-Mediated HIV-1 Stimulation; Ann NY Acad Sci 2002 973: 590-593. [Full Text] [PDF]

C. FARNIER, S. KRIEF, M. BLACHE, F. DIOT-DUPUY, G. MORY, P. FERRE, and R. BAZIN: The Signaling Pathway for ß1-Integrin/ERKs Is Involved in the Adaptation of Adipocyte Functions to Cell Size; Ann NY Acad Sci 2002 973: 594-598. [Full Text] [PDF]