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MYASTHENIA GRAVIS AND RELATED DISORDERS: Biochemical Basis for Disease of the Neuromuscular Junction

Volume 998 published September 2003
Editors:
Mark A. Agius
David P. Richman
Robert H. Fairclough
Ricardo A. Maselli
Index of Authors
Contents
Part I. Structure and Function of the Neuromuscular Junction: Physiology and Neurotransmitter Release
Part II. Structure and Function of the Neuromuscular Junction: Structure and Function of the Acetylcholine Receptor
Part III. Structure and Function of the Neuromuscular Junction: Genetic Biochemical Disorders
Part IV. Autoimmunity: General Concepts
Part V. Immunology of Autoimmune Disorders Involving the Neuron and Presynaptic Nerve Terminal
Part VI. Immunology of Postsynaptic Autoimmune Disorders: The Thymus
Part VII. Immunology of Postsynaptic Autoimmune Disorders: T Cells and Immunoregulation
Part VIII. Immunology of Postsynaptic Autoimmune Disorders: Antigenic Targets and Human Disease
Part IX. Immunology of Postsynaptic Autoimmune Disorders: Antigenic Targets and Experimental Myasthenia
Part X. Epidemiology and Measurements in Myasthenia Gravis
Part XI. Current Diagnosis and Treatment: Pre- and Postsynaptic Immune Syndromes
Part XII. Future Therapies in Myasthenia


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MARK A. AGIUS
Introduction
Ann NY Acad Sci 2003 998: xiii. [Full Text] [PDF]  

Part I. Structure and Function of the Neuromuscular Junction: Physiology and Neurotransmitter Release:
ROBERT L. RUFF
Neurophysiology of the Neuromuscular Junction: Overview
Ann NY Acad Sci 2003 998: 1-10. [Abstract] [Full Text] [PDF]  

SILVANA NUDLER, JOAQUIN PIRIZ, FRANCISCO J. URBANO, MARCELO D. ROSATO-SIRI, ERIKA S. PIEDRAS RENTERIA, and OSVALDO D. UCHITEL
Ca2+ Channels and Synaptic Transmission at the Adult, Neonatal, and P/Q-Type Deficient Neuromuscular Junction
Ann NY Acad Sci 2003 998: 11-17. [Abstract] [Full Text] [PDF]  

RICARDO A. MASELLI, WENDY BOOKS, and VANESSA DUNNE
Effect of Inherited Abnormalities of Calcium Regulation on Human Neuromuscular Transmission
Ann NY Acad Sci 2003 998: 18-28. [Abstract] [Full Text] [PDF]  

J. J. PLOMP, A. M. VAN DEN MAAGDENBERG, M. D. FERRARI, R. R. FRANTS, and P. C. MOLENAAR
Transmitter Release Deficits at the Neuromuscular Synapse of Mice with Mutations in the Cav2.1 ({alpha}1A) Subunit of the P/Q-Type Ca2+ Channel
Ann NY Acad Sci 2003 998: 29-32. [Full Text] [PDF]  

OTTAVIO CREMONA, CHIARA COLLESI, and ELISABETTA RAITERI
Protein Ubiquitylation and Synaptic Function
Ann NY Acad Sci 2003 998: 33-40. [Abstract] [Full Text] [PDF]  

Part II. Structure and Function of the Neuromuscular Junction: Structure and Function of the Acetylcholine Receptor:
JON M. LINDSTROM
Nicotinic Acetylcholine Receptors of Muscles and Nerves: Comparison of Their Structures, Functional Roles, and Vulnerability to Pathology
Ann NY Acad Sci 2003 998: 41-52. [Abstract] [Full Text] [PDF]  

ALEXANDRE MÉJAT, AYMERIC RAVEL-CHAPUIS, MARIE VANDROMME, and LAURENT SCHAEFFER
Synapse-Specific Gene Expression at the Neuromuscular Junction
Ann NY Acad Sci 2003 998: 53-65. [Abstract] [Full Text] [PDF]  

CHRISTIAN P. WANAMAKER, JOHN C. CHRISTIANSON, and WILLIAM N. GREEN
Regulation of Nicotinic Acetylcholine Receptor Assembly
Ann NY Acad Sci 2003 998: 66-80. [Abstract] [Full Text] [PDF]  

AUGUST B. SMIT, KATJUSA BREJC, NAWEED SYED, and TITIA K. SIXMA
Structure and Function of AChBP, Homologue of the Ligand-Binding Domain of the Nicotinic Acetylcholine Receptor
Ann NY Acad Sci 2003 998: 81-92. [Abstract] [Full Text] [PDF]  

SARA FUCHS, RONI KASHER, MOSHE BALASS, TALI SCHERF, MICHAL HAREL, MATI FRIDKIN, JOEL L. SUSSMAN, and EPHRAIM KATCHALSKI-KATZIR
The Binding Site of Acetylcholine Receptor: From Synthetic Peptides to Solution and Crystal Structure
Ann NY Acad Sci 2003 998: 93-100. [Abstract] [Full Text] [PDF]  

ROBERT H. FAIRCLOUGH, MARK A. AGIUS, ESWARI GUDIPATI, LAURA SILVIAN, BRENT HAMAOKA, CHRISTOPHER C. BELTZNER, MIKE Y. LIN, ANTHONY R. CHUANG, and DAVID P. RICHMAN
Agonist-Induced Transitions of the Acetylcholine Receptor
Ann NY Acad Sci 2003 998: 101-113. [Abstract] [Full Text] [PDF]  

Part III. Structure and Function of the Neuromuscular Junction: Genetic Biochemical Disorders:
DAVID BEESON, RICHARD WEBSTER, JOHN EALING, REBECCA CROXEN, SHARON BROWNLOW, MARTIN BRYDSON, JOHN NEWSOM-DAVIS, CLARKE SLATER, CHRIS HATTON, CHRIS SHELLEY, DAVID COLQUHOUN, and ANGELA VINCENT
Structural Abnormalities of the AChR Caused by Mutations Underlying Congenital Myasthenic Syndromes
Ann NY Acad Sci 2003 998: 114-124. [Abstract] [Full Text] [PDF]  

JOERN P. SIEB, SIMONE KRANER, PETER N. THOMPSON, and ORTRUD K. STEINLEIN
Congenital Myasthenic Syndrome in Cattle due to Homozygosity for a Truncating Mutation in the Acetylcholine Receptor (AChR) Epsilon-Subunit Gene
Ann NY Acad Sci 2003 998: 125-127. [Full Text] [PDF]  

STEVEN M. SINE, HAI-LONG WANG, KINJI OHNO, XIN-MING SHEN, WON YONG LEE, and ANDREW G. ENGEL
Mechanistic Diversity Underlying Fast Channel Congenital Myasthenic Syndromes
Ann NY Acad Sci 2003 998: 128-137. [Abstract] [Full Text] [PDF]  

ANDREW G. ENGEL, KINJI OHNO, XIN-MING SHEN, and STEVEN M. SINE
Congenital Myasthenic Syndromes: Multiple Molecular Targets at the Neuromuscular Junction
Ann NY Acad Sci 2003 998: 138-160. [Abstract] [Full Text] [PDF]  

Part IV. Autoimmunity: General Concepts:
JEAN-FRANÇOIS BACH
Autoimmune Diseases as the Loss of Active "Self-Control"
Ann NY Acad Sci 2003 998: 161-177. [Abstract] [Full Text] [PDF]  

JEROME B. POSNER
Immunology of Paraneoplastic Syndromes: Overview
Ann NY Acad Sci 2003 998: 178-186. [Abstract] [Full Text] [PDF]  

Part V. Immunology of Autoimmune Disorders Involving the Neuron and Presynaptic Nerve Terminal:
BETHAN LANG, ASHWIN PINTO, FEDERICA GIOVANNINI, JOHN NEWSOM-DAVIS, and ANGELA VINCENT
Pathogenic Autoantibodies in the Lambert-Eaton Myasthenic Syndrome
Ann NY Acad Sci 2003 998: 187-195. [Abstract] [Full Text] [PDF]  

KAZUO IWASA, ASHWIN PINTO, ANGELA VINCENT, and BETHAN LANG
LEMS IgG Binds to Extracellular Determinants on N-Type Voltage-Gated Calcium Channels, but Does Not Reduce VGCC Expression
Ann NY Acad Sci 2003 998: 196-199. [Full Text] [PDF]  

PAUL W. WIRTZ, NICK WILLCOX, BART O. ROEP, BETHAN LANG, AXEL R. WINTZEN, JOHN NEWSOM-DAVIS, and JAN J. VERSCHUUREN
HLA-B8 in Patients with the Lambert-Eaton Myasthenic Syndrome Reduces Likelihood of Associated Small Cell Lung Carcinoma
Ann NY Acad Sci 2003 998: 200-201. [Full Text] [PDF]  

JOHN NEWSOM-DAVIS, CAMILLA BUCKLEY, LINDA CLOVER, IAN HART, PAUL MADDISON, ERDEM TÜZÜM, and ANGELA VINCENT
Autoimmune Disorders of Neuronal Potassium Channels
Ann NY Acad Sci 2003 998: 202-210. [Abstract] [Full Text] [PDF]  

STEVEN VERNINO and VANDA A. LENNON
Neuronal Ganglionic Acetylcholine Receptor Autoimmunity
Ann NY Acad Sci 2003 998: 211-214. [Abstract] [Full Text] [PDF]  

TOBIAS LOHMANN, MARCO LONDEI, MOHAMMED HAWA, and R. DAVID G. LESLIE
Humoral and Cellular Autoimmune Responses in Stiff Person Syndrome
Ann NY Acad Sci 2003 998: 215-222. [Abstract] [Full Text] [PDF]  

Part VI. Immunology of Postsynaptic Autoimmune Disorders: The Thymus:
ALEXANDER MARX, HANS KONRAD MÜLLER-HERMELINK, and PHILIPP STRÖBEL
The Role of Thymomas in the Development of Myasthenia Gravis
Ann NY Acad Sci 2003 998: 223-236. [Abstract] [Full Text] [PDF]  

H. SHIONO, I. ROXANIS, W. ZHANG, G. P. SIMS, A. MEAGER, L. W. JACOBSON, J-L. LIU, I. MATTHEWS, Y-L. WONG, M. BONIFATI, K. MICKLEM, D. I. STOTT, J. A. TODD, D. BEESON, A. VINCENT, and N. WILLCOX
Scenarios for Autoimmunization of T and B Cells in Myasthenia Gravis
Ann NY Acad Sci 2003 998: 237-256. [Abstract] [Full Text] [PDF]  

ARNOLD I. LEVINSON, YI ZHENG, GLEN GAULTON, JONNI MOORE, C. HANK PLETCHER, DECHENG SONG, and LISA M. WHEATLEY
A New Model Linking Intrathymic Acetylcholine Receptor Expression and the Pathogenesis of Myasthenia Gravis
Ann NY Acad Sci 2003 998: 257-265. [Abstract] [Full Text] [PDF]  

ROZEN LE PANSE-RUSKONÉ and SONIA BERRIH-AKNIN
Human Myoid Cells Protect Thymocytes from Apoptosis
Ann NY Acad Sci 2003 998: 266-269. [Full Text] [PDF]  

LAURA PASSERINI, PIA BERNASCONI, FULVIO BAGGI, FERDINANDO CORNELIO, and RENATO MANTEGAZZA
Analysis of SjTREC Levels in Thymus from MG Patients and Normal Children
Ann NY Acad Sci 2003 998: 270-274. [Full Text] [PDF]  

A. BALANDINA, A. SAOUDI, P. DARTEVELLE, and S. BERRIH-AKNIN
Analysis of CD4+CD25+ Cell Population in the Thymus from Myasthenia Gravis Patients
Ann NY Acad Sci 2003 998: 275-277. [Abstract] [Full Text] [PDF]  

PIA BERNASCONI, LAURA PASSERINI, ANDREA ANNONI, FEDERICA UBIALI, CRISTIANA MARCOZZI, PAOLO CONFALONIERI, FERDINANDO CORNELIO, and RENATO MANTEGAZZA
Expression of Transforming Growth Factor-ß1 in Thymus of Myasthenia Gravis Patients: Correlation with Pathological Abnormalities
Ann NY Acad Sci 2003 998: 278-283. [Full Text] [PDF]  

Part VII. Immunology of Postsynaptic Autoimmune Disorders: T Cells and Immunoregulation:
MONICA MILANI, NORMA OSTLIE, WEI WANG, and BIANCA M. CONTI-FINE
T Cells and Cytokines in the Pathogenesis of Acquired Myasthenia Gravis
Ann NY Acad Sci 2003 998: 284-307. [Abstract] [Full Text] [PDF]  

M. DE BAETS, M. STASSEN, M. LOSEN, X. ZHANG, and B. MACHIELS
Immunoregulation in Experimental Autoimmune Myasthenia Gravis—about T Cells, Antibodies, and Endplates
Ann NY Acad Sci 2003 998: 308-317. [Abstract] [Full Text] [PDF]  

Y. HUANG, R. PIRSKANEN, R. CISCOMBE, H. LINK, and A-K. LEFVERT
Circulating CD4+CD25+ and CD4+CD25- T Cells in Myasthenia Gravis
Ann NY Acad Sci 2003 998: 318-319. [Full Text] [PDF]  

F. JAMBOU, M. MENESTRIER, I. KLINGEL-SCHMITT, S. CAILLAT-ZUCMAN, A. AÏSSAOUI, S. BERRIH-AKNIN, and S. COHEN-KAMINSKY
Rationale for a T Cell Receptor Peptide Therapy in Myasthenia Gravis
Ann NY Acad Sci 2003 998: 320-323. [Full Text] [PDF]  

Part VIII. Immunology of Postsynaptic Autoimmune Disorders: Antigenic Targets and Human Disease:
ANGELA VINCENT, JOHN McCONVILLE, MARIA ELENA FARRUGIA, JOHN BOWEN, PAUL PLESTED, TERESA TANG, AMELIA EVOLI, IAN MATTHEWS, GARY SIMS, PAOLA DALTON, LESLIE JACOBSON, AGATA POLIZZI, FRANS BLAES, BETHAN LANG, DAVID BEESON, NICK WILLCOX, JOHN NEWSOM-DAVIS, and WERNER HOCH
Antibodies in Myasthenia Gravis and Related Disorders
Ann NY Acad Sci 2003 998: 324-335. [Abstract] [Full Text] [PDF]  

SAMIA RAGHEB and ROBERT P. LISAK
Differences between the {epsilon} and {gamma} Subunits of the Acetylcholine Receptor (AChR) May Be Significant in Autoimmune Myasthenia Gravis
Ann NY Acad Sci 2003 998: 336-338. [Full Text] [PDF]  

UDAY KISHORE, WEI ZHANG, LOUISE CORLETT, PATRICK WATERS, NICOLAS GLAICHENHAUS, and NICK WILLCOX
Use of Peptide:HLA Class II Complexes to Study Specific T Cells in Autoimmune Myasthenia Gravis
Ann NY Acad Sci 2003 998: 339-342. [Full Text] [PDF]  

GEIR OLVE SKEIE, FREDRIK ROMI, JOHAN A. AARLI, PÅL TORE BENTSEN, and NILS ERIK GILHUS
Pathogenesis of Myositis and Myasthenia Associated with Titin and Ryanodine Receptor Antibodies
Ann NY Acad Sci 2003 998: 343-350. [Abstract] [Full Text] [PDF]  

MIRTA MIHOVILOVIC, EMMA CIAFALONI, JENNIFER BUTTERWORTH-ROBINETTE, JIAN-PING JIN, JANICE MASSEY, and DONALD B. SANDERS
Antibodies in Sera of Patients with Late-Onset Myasthenia Gravis Recognize the PEVK Domain of Titin
Ann NY Acad Sci 2003 998: 351-355. [Full Text] [PDF]  

EMANUELA BARTOCCIONI, MARIAPAOLA MARINO, AMELIA EVOLI, MARCUS A. RUEGG, FLAVIA SCUDERI, and CARLO PROVENZANO
Identification of Disease-Specific Autoantibodies in Seronegative Myasthenia Gravis
Ann NY Acad Sci 2003 998: 356-358. [Full Text] [PDF]  

STEVEN VERNINO and VANDA A. LENNON
Muscle and Neuronal Autoantibody Markers of Thymoma: Neurological Correlations
Ann NY Acad Sci 2003 998: 359-361. [Full Text] [PDF]  

HENRY J. KAMINSKI, ZHUYI LI, CHELLIAH RICHMONDS, ROBERT L. RUFF, and LINDA KUSNER
Susceptibility of Ocular Tissues to Autoimmune Diseases
Ann NY Acad Sci 2003 998: 362-374. [Abstract] [Full Text] [PDF]  

Part IX. Immunology of Postsynaptic Autoimmune Disorders: Antigenic Targets and Experimental Myasthenia:
HUAN YANG, ELZBIETA GOLUSZKO, CHELLA DAVID, DAVID K. OKITA, BIANCA CONTI-FINE, TEH-SHENG CHAN, MATHILDE A. POUSSIN, and PREMKUMAR CHRISTADOSS
Induction of Myasthenia Gravis in HLA Transgenic Mice by Immunization with Human Acetylcholine Receptors
Ann NY Acad Sci 2003 998: 375-378. [Abstract] [Full Text] [PDF]  

ALEXEI MIAGKOV, ADRIAN A. LOBITO, BINGZHI YANG, MARCELA F. LOPES, ROBERT N. ADAMS, GREGORY R. PALARDY, MICHELE M. JOHNSON, HUGH I. McFARLAND, MICHAEL J. LENARDO, and DANIEL B. DRACHMAN
Production and Characterization of a T Cell Receptor Transgenic Mouse Recognizing the Immunodominant Epitope of the Torpedo californica Acetylcholine Receptor
Ann NY Acad Sci 2003 998: 379-383. [Full Text] [PDF]  

WEI WANG, MONICA MILANI, DAVID OKITA, NORMA OSTLIE, and BIANCA M. CONTI-FINE
Epitope Repertoire of Th1 and Th2 Cells Reactive with the Mouse Muscle AChR {alpha} Subunit in C57Bl/6 Mice
Ann NY Acad Sci 2003 998: 384-387. [Full Text] [PDF]  

TALI FEFERMAN, SIN-HYEOG IM, SARA FUCHS, and MIRIAM C. SOUROUJON
Epitope Spreading to Hidden Cytoplasmic Regions of the Acetylcholine Receptor in Experimental Autoimmune Myasthenia Gravis
Ann NY Acad Sci 2003 998: 388-390. [Full Text] [PDF]  

FULVIO BAGGI, ANDREA ANNONI, FEDERICA UBIALI, RENATO LONGHI, MONICA MILANI, RENATO MANTEGAZZA, FERDINANDO CORNELIO, and CARLO ANTOZZI
Immunization with Rat-, but Not Torpedo-Derived 97-116 Peptide of the AChR {alpha}-Subunit Induces Experimental Myasthenia Gravis in Lewis Rat
Ann NY Acad Sci 2003 998: 391-394. [Full Text] [PDF]  

FULVIO BAGGI, ANDREA ANNONI, FEDERICA UBIALI, RENATO LONGHI, RENATO MANTEGAZZA, FERDINANDO CORNELIO, and CARLO ANTOZZI
Effect on T Cell Recognition and Immunogenicity of Alanine-Substituted Peptides Corresponding to 97-116 Sequence of the Rat AChR {alpha}-Subunit
Ann NY Acad Sci 2003 998: 395-398. [Full Text] [PDF]  

MAURICE H. W. STASSEN, BARBIE M. MACHIELS, EFROSINI FOSTIERI, SOCRATES J. TZARTOS, SONIA BERRIH-AKNIN, EUGÈNE BOSMANS, PAUL W. H. I. PARREN, and MARC H. DE BAETS
Characterization of a Fully Human IgG1 Reconstructed from an Anti-AChR Fab
Ann NY Acad Sci 2003 998: 399-400. [Full Text] [PDF]  

R. W.M. BULLENS, G. M. O'HANLON, E. WAGNER, P. C. MOLENAAR, KOICHI FURUKAWA, KEIKO FURUKAWA, J. J. PLOMP, and H. J. WILLISON
Roles of Complex Gangliosides at the Neuromuscular Junction
Ann NY Acad Sci 2003 998: 401-403. [Full Text] [PDF]  

M. S. SONS, M. VERHAGE, and J. J. PLOMP
Role of Munc18-1 in Synaptic Plasticity at the Myasthenic Neuromuscular Junction
Ann NY Acad Sci 2003 998: 404-406. [Full Text] [PDF]  

Part X. Epidemiology and Measurements in Myasthenia Gravis:
LAWRENCE H. PHILLIPS, II
The Epidemiology of Myasthenia Gravis
Ann NY Acad Sci 2003 998: 407-412. [Abstract] [Full Text] [PDF]  

RENATO MANTEGAZZA, FULVIO BAGGI, CARLO ANTOZZI, PAOLO CONFALONIERI, LUCIA MORANDI, PIA BERNASCONI, FRANCESCA ANDREETTA, ORNELLA SIMONCINI, ANGELA CAMPANELLA, ETTORE BEGHI, and FERDINANDO CORNELIO
Myasthenia Gravis (MG): Epidemiological Data and Prognostic Factors
Ann NY Acad Sci 2003 998: 413-423. [Abstract] [Full Text] [PDF]  

JOHAN A. AARLI, FREDRIK ROMI, GEIR OLVE SKEIE, and NILS ERIK GILHUS
Myasthenia Gravis in Individuals over 40
Ann NY Acad Sci 2003 998: 424-431. [Abstract] [Full Text] [PDF]  

RICHARD J. BAROHN
Standards of Measurements in Myasthenia Gravis
Ann NY Acad Sci 2003 998: 432-439. [Abstract] [Full Text] [PDF]  

DONALD B. SANDERS, BERNADETTE TUCKER-LIPSCOMB, and JANICE M. MASSEY
A Simple Manual Muscle Test for Myasthenia Gravis: Validation and Comparison with the QMG Score
Ann NY Acad Sci 2003 998: 440-444. [Full Text] [PDF]  

P. GAJDOS, T. SHARSHAR, and S. CHEVRET
Standards of Measurements in Myasthenia Gravis
Ann NY Acad Sci 2003 998: 445-452. [Abstract] [Full Text] [PDF]  

Part XI. Current Diagnosis and Treatment: Pre- and Postsynaptic Immune Syndromes:
MARK A. AGIUS, DAVID P. RICHMAN, ROBERT H. FAIRCLOUGH, JOHAN AARLI, NILS ERIK GILHUS, and FREDRIK ROMI
Three Forms of Immune Myasthenia
Ann NY Acad Sci 2003 998: 453-456. [Abstract] [Full Text] [PDF]  

DAVID P. RICHMAN and MARK A. AGIUS
Treatment Principles in the Management of Autoimmune Myasthenia Gravis
Ann NY Acad Sci 2003 998: 457-472. [Abstract] [Full Text] [PDF]  

GIL I. WOLFE, HENRY J. KAMINSKI, ALFRED JARETZKI, III, ANTHONY SWAN, and JOHN NEWSOM-DAVIS
Development of a Thymectomy Trial in Nonthymomatous Myasthenia Gravis Patients Receiving Immunosuppressive Therapy
Ann NY Acad Sci 2003 998: 473-480. [Abstract] [Full Text] [PDF]  

FREDRIK ROMI, NILS E. GILHUS, JAN E. VARHAUG, ANDREAS MYKING, GEIR O. SKEIE, and JOHAN A. AARLI
Thymectomy and Antimuscle Antibodies in Nonthymomatous Myasthenia Gravis
Ann NY Acad Sci 2003 998: 481-490. [Abstract] [Full Text] [PDF]  

JOSÉ FRANCISCO TÉLLEZ-ZENTENO, JOSE MARÍA REMES-TROCHE, GUILLERMO GARCÍA-RAMOS, BRUNO ESTAÑOL, and JUAN GARDUÑO-ESPINOZA
Prognostic Factors of Thymectomy in Patients with Myasthenia Gravis: A Cohort of 132 Patients
Ann NY Acad Sci 2003 998: 491-493. [Full Text] [PDF]  

MATTHEW N. MERIGGIOLI, JULIE ROWIN, JUDITH G. RICHMAN, and SUE LEURGANS
Mycophenolate Mofetil for Myasthenia Gravis A Double-Blind, Placebo-Controlled Pilot Study
Ann NY Acad Sci 2003 998: 494-499. [Abstract] [Full Text] [PDF]  

DONALD B. SANDERS
Lambert-Eaton Myasthenic Syndrome: Diagnosis and Treatment
Ann NY Acad Sci 2003 998: 500-508. [Abstract] [Full Text] [PDF]  

RUDY MERCELIS
Abnormal Single-Fiber Electromyography in Patients Not Having Myasthenia: Risk for Diagnostic Confusion?
Ann NY Acad Sci 2003 998: 509-511. [Full Text] [PDF]  

Part XII. Future Therapies in Myasthenia:
INGO H. TARNER, ANTHONY J. SLAVIN, JACQUELINE McBRIDE, ALENKA LEVICNIK, RICHARD SMITH, GARRY P. NOLAN, CHRISTOPHER H. CONTAG, and C. GARRISON FATHMAN
Treatment of Autoimmune Disease by Adoptive Cellular Gene Therapy
Ann NY Acad Sci 2003 998: 512-519. [Abstract] [Full Text] [PDF]  

D. B. DRACHMAN, J-M. WU, A. MIAGKOV, M. A. WILLIAMS, R. N. ADAMS, and B. WU
Specific Immunotherapy of Experimental Myasthenia by Genetically Engineered APCs: The "Guided Missile" Strategy
Ann NY Acad Sci 2003 998: 520-532. [Abstract] [Full Text] [PDF]  

MIRIAM C. SOUROUJON, PRASANTA K. MAITI, TALI FEFERMAN, SIN-HYEOG IM, LILY RAVEH, and SARA FUCHS
Suppression of Myasthenia Gravis by Antigen-Specific Mucosal Tolerance and Modulation of Cytokines and Costimulatory Factors
Ann NY Acad Sci 2003 998: 533-536. [Abstract] [Full Text] [PDF]  

H. LINK, Y. M. HUANG, and B. XIAO
Suppression of EAMG in Lewis Rats by IL-10-Exposed Dendritic Cells
Ann NY Acad Sci 2003 998: 537-538. [Full Text] [PDF]  

LOUKIA PSARIDI-LINARDAKI, AVGI MAMALAKI, and SOCRATES J. TZARTOS
Future Therapeutic Strategies in Autoimmune Myasthenia Gravis
Ann NY Acad Sci 2003 998: 539-548. [Abstract] [Full Text] [PDF]  

To see an article, click its [Full Text] or [PDF] link. To review many abstracts, check the boxes to the left of the titles you want, and click the 'Get All Checked Abstract(s)' button. To see one abstract at a time, click its [Abstract] link.

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