Annals of the New York Academy of Science
The Applications of Bioinformatics in Cancer Detection
Volume 1020 (Est. pub. date May 2004)

Editors:
Asad Umar, Izet Kapetanovic, and Javed Khan

Note: This volume is the result of the Applications of Bioinformatics in Cancer Detection Workshop, sponsored by the Division of Cancer Prevention, National Cancer Institute, National Institutes of Health, and held August 6-7, 2002, in Bethesda, Maryland.

Preface

Part I. Introduction

Part II. Genomics and Proteomics in Early Cancer Detection and Classification

Part III. Bioinformatics in Drug Discovery

Part IV. Glossary

Preface

Peter Greenwald

Preface

Ann NY Acad Sci 2004; 1020: ix

Part I. Introduction

Izet M. Kapetanovic, Asad Umar, and Javed Khan

Proceedings: The Applications of Bioinformatics in Cancer Detection Workshop

Ann NY Acad Sci 2004; 1020: 1

Izet M. Kapetanovic, Simon Rosenfeld, and Grant Izmirlian

Overview of Commonly Used Bioinformatics Methods and Their Applications

Ann NY Acad Sci 2004; 1020: 10

Part II. Genomics and Proteomics in Early Cancer Detection and Classification

Simon Rosenfeld

New Developments in Cancer-Related Computational Statistics

Ann NY Acad Sci 2004; 1020: 22

Daniel R. Rhodes and Arul M. Chinnaiyan

Bioinformatics Strategies for Translating Genome-Wide Expression Analyses into Clinically Useful Cancer Markers

Ann NY Acad Sci 2004; 1020: 32

Mahlet G. Tadesse and Joseph G. Ibrahim

A Bayesian Hierarchical Model for the Analysis of Affymetrix Arrays

Ann NY Acad Sci 2004; 1020: 41

Braden T. Greer and Javed Khan

Diagnostic Classification of Cancer Using DNA Microarrays and Artificial Intelligence

Ann NY Acad Sci 2004; 1020: 49

Howard H. Yang and Maxwell P. Lee

Application of Bioinformatics in Cancer Epigenetics

Ann NY Acad Sci 2004; 1020: 67

Carl F. Schaefer

Pathway Databases

Ann NY Acad Sci 2004; 1020: 77

Ernest S. Kawasaki

Microarrays and the Gene Expression Profile of a Single Cell

Ann NY Acad Sci 2004; 1020: 92

Robert J. Clifford, Michael N. Edmonson, Cu Nguyen, Titia Scherpbier, Ying Hu, and Kenneth H. Buetow

Bioinformatics Tools for Single Nucleotide Polymorphism Discovery and Analysis

Ann NY Acad Sci 2004; 1020: 101

Simon Rosenfeld, Thomas Wang, Young Kim, and John Milner

Numerical Deconvolution of cDNA Microarray Signal: Simulation Study

Ann NY Acad Sci 2004; 1020: 110

Robert F. Murphy

Automated Interpretation of Protein Subcellular Location Patterns: Implications for Early Cancer Detection and Assessment

Ann NY Acad Sci 2004; 1020: 124

Data-Driven Computer Simulation of Human Cancer Cell

Ann NY Acad Sci 2004; 1020: 132

Grant Izmirlian

Application of the Random Forest Classification Algorithm to a SELDI-TOF Proteomics Study in the Setting of a Cancer Prevention Trial

Ann NY Acad Sci 2004; 1020: 154

Matthew Freedman

Improved Small Volume Lung Cancer Detection with Computer-Aided Detection: Database Characteristics and Imaging of Response to Breast Cancer Risk Reduction Strategies

Ann NY Acad Sci 2004; 1020: 175

Carlos Andres Pena-Reyes

Evolutionary Fuzzy Modeling Human Diagnostic Decisions

Ann NY Acad Sci 2004; 1020: 190

Michael F. Ochs, Thomas D. Moloshok, Ghislain Bidaut, and Garabet Toby

Bayesian Decomposition: Analyzing Microarray Data within a Biological Context

Ann NY Acad Sci 2004; 1020: 212

Part III. Bioinformatics in Drug Discovery

Ganesh Vaidyanathan

InfoEvolve{tm}: Moving from Data to Knowledge Using Information Theory and Genetic Algorithms

Ann NY Acad Sci 2004; 1020: 227

John F. McCarthy, Kenneth A. Marx, Patrick E. Hoffman, Alexander G. Gee, Philip O?Neil, M. L. Ujwal, and John Hotchkiss

Applications of Machine Learning and High-Dimensional Visualization in Cancer Detection, Diagnosis, and Management

Ann NY Acad Sci 2004; 1020: 239

Part IV. Glossary

Asad Umar

Applications of Bioinformatics in Cancer Detection: A Lexicon of Bioinformatics

Ann NY Acad Sci 2004; 1020: 263